Functional and Clinical Impact of CircRNAs in Oral Cancer
The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summ...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-04-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/4/1041 |
| _version_ | 1797569902401290240 |
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| author | Ion Cristóbal Cristina Caramés Jaime Rubio Marta Sanz-Alvarez Melani Luque Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas |
| author_facet | Ion Cristóbal Cristina Caramés Jaime Rubio Marta Sanz-Alvarez Melani Luque Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas |
| author_sort | Ion Cristóbal |
| collection | DOAJ |
| description | The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summarizes and puts into context the existing literature in order to clarify the relevance of circRNAs as novel mediators of oral cancer pathogenesis as well as their potential usefulness as predictors of clinical outcome and response to therapy in this disease. |
| first_indexed | 2024-03-10T20:16:55Z |
| format | Article |
| id | doaj.art-eeaa61ff9cb9457ab86356d10070f04b |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T20:16:55Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-eeaa61ff9cb9457ab86356d10070f04b2023-11-19T22:29:54ZengMDPI AGCancers2072-66942020-04-01124104110.3390/cancers12041041Functional and Clinical Impact of CircRNAs in Oral CancerIon Cristóbal0Cristina Caramés1Jaime Rubio2Marta Sanz-Alvarez3Melani Luque4Juan Madoz-Gúrpide5Federico Rojo6Jesús García-Foncillas7Cancer Unit for Research on Novel Therapeutic Targets, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainCancer Unit for Research on Novel Therapeutic Targets, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainCancer Unit for Research on Novel Therapeutic Targets, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainPathology Department, IIS- Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainPathology Department, IIS- Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainPathology Department, IIS- Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainPathology Department, IIS- Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainTranslational Oncology Division, Oncohealth Institute, IIS- Fundación Jiménez Díaz-UAM, E-28040 Madrid, SpainThe increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summarizes and puts into context the existing literature in order to clarify the relevance of circRNAs as novel mediators of oral cancer pathogenesis as well as their potential usefulness as predictors of clinical outcome and response to therapy in this disease.https://www.mdpi.com/2072-6694/12/4/1041circRNAsignalingdiagnosisprognosisoral cancer |
| spellingShingle | Ion Cristóbal Cristina Caramés Jaime Rubio Marta Sanz-Alvarez Melani Luque Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas Functional and Clinical Impact of CircRNAs in Oral Cancer Cancers circRNA signaling diagnosis prognosis oral cancer |
| title | Functional and Clinical Impact of CircRNAs in Oral Cancer |
| title_full | Functional and Clinical Impact of CircRNAs in Oral Cancer |
| title_fullStr | Functional and Clinical Impact of CircRNAs in Oral Cancer |
| title_full_unstemmed | Functional and Clinical Impact of CircRNAs in Oral Cancer |
| title_short | Functional and Clinical Impact of CircRNAs in Oral Cancer |
| title_sort | functional and clinical impact of circrnas in oral cancer |
| topic | circRNA signaling diagnosis prognosis oral cancer |
| url | https://www.mdpi.com/2072-6694/12/4/1041 |
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