Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology

Acute biliary diseases have become the most common indication for major abdominal surgery. We investigated 60 patients who underwent surgery for the acute biliary diseases, within 48 hours from the onset of the illness (group I), and over longer preoperative interval (48 h up to 5 days) (group II)....

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Main Authors: Karamarković Aleksandar R., Popović Nada, Bajec Đorđe, Jeremić Vasilije, Đukić Vladimir, Radenković Dejan, Bumbaširević Vesna, Gregorić Pavle
Format: Article
Language:English
Published: Serbian Medical Society 2005-01-01
Series:Srpski Arhiv za Celokupno Lekarstvo
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790502052K.pdf
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author Karamarković Aleksandar R.
Popović Nada
Bajec Đorđe
Jeremić Vasilije
Đukić Vladimir
Radenković Dejan
Bumbaširević Vesna
Gregorić Pavle
author_facet Karamarković Aleksandar R.
Popović Nada
Bajec Đorđe
Jeremić Vasilije
Đukić Vladimir
Radenković Dejan
Bumbaširević Vesna
Gregorić Pavle
author_sort Karamarković Aleksandar R.
collection DOAJ
description Acute biliary diseases have become the most common indication for major abdominal surgery. We investigated 60 patients who underwent surgery for the acute biliary diseases, within 48 hours from the onset of the illness (group I), and over longer preoperative interval (48 h up to 5 days) (group II). Surgical specimen (gallbladder) was histologically examined. Samples for microbiological exams were obtained from gallbladder, common bile duct, Lund's node, gallbladder bed and peritoneal cavity. Positive bile cultures were found in 43% of group I, and in 70% of group II (p<0.05). Microbiological analysis revealed 13 different species, mostly Gram negative aerobic rods (69%). The incidence of bacteriobilia was in correlation with HP of lesions (79% in the acute and 18% in chronic lesions; p<0.01), what testified the importance of time interval and role of bacterial factor in the acute biliary pathology. Septic complications strictly occurred in patients with positive biliary findings. Early surgical treatment eliminates focus, and stops further development of intraabdominal and systemic septic complications. Correlation between bacteriobilia and septic sequelae calls for prophylactic use of antibiotics.
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spelling doaj.art-eeab72429de144cb8b71b66153d21e732022-12-21T20:22:11ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792005-01-011331-2525710.2298/SARH0502052KRelation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathologyKaramarković Aleksandar R.Popović NadaBajec ĐorđeJeremić VasilijeĐukić VladimirRadenković DejanBumbaširević VesnaGregorić PavleAcute biliary diseases have become the most common indication for major abdominal surgery. We investigated 60 patients who underwent surgery for the acute biliary diseases, within 48 hours from the onset of the illness (group I), and over longer preoperative interval (48 h up to 5 days) (group II). Surgical specimen (gallbladder) was histologically examined. Samples for microbiological exams were obtained from gallbladder, common bile duct, Lund's node, gallbladder bed and peritoneal cavity. Positive bile cultures were found in 43% of group I, and in 70% of group II (p<0.05). Microbiological analysis revealed 13 different species, mostly Gram negative aerobic rods (69%). The incidence of bacteriobilia was in correlation with HP of lesions (79% in the acute and 18% in chronic lesions; p<0.01), what testified the importance of time interval and role of bacterial factor in the acute biliary pathology. Septic complications strictly occurred in patients with positive biliary findings. Early surgical treatment eliminates focus, and stops further development of intraabdominal and systemic septic complications. Correlation between bacteriobilia and septic sequelae calls for prophylactic use of antibiotics.http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790502052K.pdfbacteriobiliaacute biliary pathologybiliary infection
spellingShingle Karamarković Aleksandar R.
Popović Nada
Bajec Đorđe
Jeremić Vasilije
Đukić Vladimir
Radenković Dejan
Bumbaširević Vesna
Gregorić Pavle
Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
Srpski Arhiv za Celokupno Lekarstvo
bacteriobilia
acute biliary pathology
biliary infection
title Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
title_full Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
title_fullStr Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
title_full_unstemmed Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
title_short Relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
title_sort relation of pathoanatomic substrate and incidence of bacterial infection in the acute biliary pathology
topic bacteriobilia
acute biliary pathology
biliary infection
url http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790502052K.pdf
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