Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China

Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China

Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can...

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Bibliographic Details
Main Authors: Yu Huang, Li Guo, Yanan Li, Lili Ren, Jiqin Nie, Fengwen Xu, Tingxuan Huang, Jingchuan Zhong, Zhangling Fan, Yin Zhang, Yu Xie, Qiao Zhang, Shan Mei, Yan Xiao, Xinming Wang, Liuhui Xu, Fei Guo, Jianwei Wang
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2024-02-01
Series:Emerging Infectious Diseases
Subjects:
vaccinia virus
smallpox
mpox
monkeypox
viruses
neutralizing antibodies
Online Access:https://wwwnc.cdc.gov/eid/article/30/2/23-0542_article
Description
Summary:Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can help guide mpox vaccination strategies in China.
ISSN:1080-6040
1080-6059

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