MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation

MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation

Abstract Background MicroRNAs (miRNAs) are critical regulators in osteogenesis and cartilage formation. This study was designed to investigate whether miR-532-5p plays a role in the regulation of osteoporosis. Methods Osteoporotic fractures (OP group, n = 10) or osteoarthritis without osteoporosis (...

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Bibliographic Details
Main Authors: Xinyu Guo, Shijun Wei, Feng Xu, Xianhua Cai, Huasong Wang, Ran Ding
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
miR-532-5p
FOXO1
Osteoporosis
Osteogenic differentiation
Online Access:http://link.springer.com/article/10.1186/s12891-020-03317-y

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