Zinc Metalloprotease ProA from <i>Legionella pneumophila</i> Inhibits the Pro-Inflammatory Host Response by Degradation of Bacterial Flagellin

Zinc Metalloprotease ProA from <i>Legionella pneumophila</i> Inhibits the Pro-Inflammatory Host Response by Degradation of Bacterial Flagellin

The environmental bacterium <i>Legionella pneumophila</i> is an intracellular pathogen of various protozoan hosts and able to cause Legionnaires’ disease, a severe pneumonia in humans. By encoding a wide selection of virulence factors, the infectious agent possesses several strategies to...

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Bibliographic Details
Main Authors: Lina Scheithauer, Stefanie Thiem, Can M. Ünal, Ansgar Dellmann, Michael Steinert
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
<i>L. pneumophila</i>
ProA
FlaA
human lung tissue explants
TLR5
Online Access:https://www.mdpi.com/2218-273X/12/5/624

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