Study protocol for a randomised placebo controlled trial of platelet-rich plasma injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction

Study protocol for a randomised placebo controlled trial of platelet-rich plasma injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction

Introduction The elevated cytokine levels in patients suffering from anterior cruciate ligament (ACL) rupture may lead to acute post-traumatic arthritis (APTA) and post-traumatic osteoarthritis (PTOA). Due to its chondrogenerative and anti-inflammatory effect, platelet-rich plasma (PRP) therapy is e...

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Bibliographic Details
Main Authors:	Masashi Nagao, Yoshitomo Saita, Muneaki Ishijima, Yohei Kobayashi, Keiji Kobayashi, Haruka Kaneko, Hirofumi Nishio, Yasumasa Momoi, Ryosuke Nakajima, Sayuri Uchino, Takanori Wakayama, Shin Fukusato, Suguru Wakana, Jun Tomura, Keiichi Yoshida, Mitsuaki Kubota
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2022-11-01
Series:	BMJ Open
Online Access:	https://bmjopen.bmj.com/content/12/11/e061484.full

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