The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease
Mengqing Xiong,1 Weihua Hu,1 Minglin Dong,1 Meifang Wang,2 Junwen Chen,3 Hanzhong Xiong,4 Minhua Zhong,5 Yan Jiang,6 Dan Liu,6 Ke Hu1 1Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, People’s Republic of China; 2Department of Respira...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-11-01
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| Series: | International Journal of COPD |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-screening-value-of-ess-sacs-bq-and-sbq-on-obstructive-sleep-apnea--peer-reviewed-article-COPD |
| _version_ | 1818562204179365888 |
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| author | Xiong M Hu W Dong M Wang M Chen J Xiong H Zhong M Jiang Y Liu D Hu K |
| author_facet | Xiong M Hu W Dong M Wang M Chen J Xiong H Zhong M Jiang Y Liu D Hu K |
| author_sort | Xiong M |
| collection | DOAJ |
| description | Mengqing Xiong,1 Weihua Hu,1 Minglin Dong,1 Meifang Wang,2 Junwen Chen,3 Hanzhong Xiong,4 Minhua Zhong,5 Yan Jiang,6 Dan Liu,6 Ke Hu1 1Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Xiangyang Hospital, Hubei University of Medicine, Xiangyang 441000, People’s Republic of China; 4Department of Respiratory and Critical Care Medicine, Ezhou Central Hospital, Ezhou 436000, People’s Republic of China; 5Department of Respiratory and Critical Care Medicine, Xiaogan Central Hospital, Wuhan University of Technology, Xiaogan 432000, People’s Republic of China; 6Division of Respiratory Disease, The Fifth Hospital of Wuhan City, Wuhan 430050, People’s Republic of ChinaCorrespondence: Ke HuDepartment of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Zhangzhidong Road, No. 99, Wuhan 430060, People’s Republic of ChinaTel +86 189 7103 5988Fax +86 27 8804 2292Email huke-rmhospital@163.comObjective: To compare the performance of Epworth sleepiness scale (ESS), sleep apnea clinical score (SACS), Berlin questionnaire (BQ), and STOP-BANG questionnaire (SBQ) in screening for obstructive sleep apnea (OSA) in patients with chronic obstructive pulmonary disease (COPD).Methods: A total of 431 patients were analyzed. All subjects completed lung function test, ESS, SACS, BQ, and SBQ survey and overnight polysomnography (PSG). According to lung function and PSG results, participants were divided into COPD with OSA group (OVS, AHI ≥5) and without OSA group (AHI <5). The value of ESS, SACS, BQ, and SBQ was compared in predicting OSA in patients with COPD by receiver-operating characteristic (ROC) curve statistics.Results: Of the 431 subjects, there were 96 cases in COPD without OSA group, and 335 cases in OVS group including 183, 96, and 56 cases of COPD combined with mild, moderate or severe OSA. In predicting different degrees of severity of OSA in patients with COPD, the value of ESS was poor with all the values of area under the curve (AUC) < 0.7. SACS and BQ had moderate predictive value in screening for severe OSA with the value of AUC of 0.750, 0.735 respectively. However, the SBQ performed best in predicting various degrees of OSA. For screening mild OSA (AHI ≥5), the ROC statistics recommended the cut-off score of SBQ >2 was considered high risk of OSA; the sensitivity, specificity, and AUC were 92.8%, 40.6%, and 0.723 respectively, the odds ratio (OR) was 2.161. When AHI ≥15, AUC for SBQ was 0.737. In predicting severe OSA (AHI ≥30), the ROC curve showed cut-off point, sensitivity, specificity, and AUC for SBQ was >4, 66.1%, 82.1%, and 0.824 respectively; the positive and negative likelihood ratio was 3.70, 0.41 separately, the OR was 2.977.Conclusion: SBQ performed better than ESS, SACS, and BQ in predicting OSA in patients with COPD.Keywords: Berlin questionnaire, STOP-BANG questionnaire |
| first_indexed | 2024-12-14T01:00:38Z |
| format | Article |
| id | doaj.art-eeaf5b33a57243d0b1883f9e678f911a |
| institution | Directory Open Access Journal |
| issn | 1178-2005 |
| language | English |
| last_indexed | 2024-12-14T01:00:38Z |
| publishDate | 2019-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj.art-eeaf5b33a57243d0b1883f9e678f911a2022-12-21T23:23:16ZengDove Medical PressInternational Journal of COPD1178-20052019-11-01Volume 142497250549739The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary DiseaseXiong MHu WDong MWang MChen JXiong HZhong MJiang YLiu DHu KMengqing Xiong,1 Weihua Hu,1 Minglin Dong,1 Meifang Wang,2 Junwen Chen,3 Hanzhong Xiong,4 Minhua Zhong,5 Yan Jiang,6 Dan Liu,6 Ke Hu1 1Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Xiangyang Hospital, Hubei University of Medicine, Xiangyang 441000, People’s Republic of China; 4Department of Respiratory and Critical Care Medicine, Ezhou Central Hospital, Ezhou 436000, People’s Republic of China; 5Department of Respiratory and Critical Care Medicine, Xiaogan Central Hospital, Wuhan University of Technology, Xiaogan 432000, People’s Republic of China; 6Division of Respiratory Disease, The Fifth Hospital of Wuhan City, Wuhan 430050, People’s Republic of ChinaCorrespondence: Ke HuDepartment of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Zhangzhidong Road, No. 99, Wuhan 430060, People’s Republic of ChinaTel +86 189 7103 5988Fax +86 27 8804 2292Email huke-rmhospital@163.comObjective: To compare the performance of Epworth sleepiness scale (ESS), sleep apnea clinical score (SACS), Berlin questionnaire (BQ), and STOP-BANG questionnaire (SBQ) in screening for obstructive sleep apnea (OSA) in patients with chronic obstructive pulmonary disease (COPD).Methods: A total of 431 patients were analyzed. All subjects completed lung function test, ESS, SACS, BQ, and SBQ survey and overnight polysomnography (PSG). According to lung function and PSG results, participants were divided into COPD with OSA group (OVS, AHI ≥5) and without OSA group (AHI <5). The value of ESS, SACS, BQ, and SBQ was compared in predicting OSA in patients with COPD by receiver-operating characteristic (ROC) curve statistics.Results: Of the 431 subjects, there were 96 cases in COPD without OSA group, and 335 cases in OVS group including 183, 96, and 56 cases of COPD combined with mild, moderate or severe OSA. In predicting different degrees of severity of OSA in patients with COPD, the value of ESS was poor with all the values of area under the curve (AUC) < 0.7. SACS and BQ had moderate predictive value in screening for severe OSA with the value of AUC of 0.750, 0.735 respectively. However, the SBQ performed best in predicting various degrees of OSA. For screening mild OSA (AHI ≥5), the ROC statistics recommended the cut-off score of SBQ >2 was considered high risk of OSA; the sensitivity, specificity, and AUC were 92.8%, 40.6%, and 0.723 respectively, the odds ratio (OR) was 2.161. When AHI ≥15, AUC for SBQ was 0.737. In predicting severe OSA (AHI ≥30), the ROC curve showed cut-off point, sensitivity, specificity, and AUC for SBQ was >4, 66.1%, 82.1%, and 0.824 respectively; the positive and negative likelihood ratio was 3.70, 0.41 separately, the OR was 2.977.Conclusion: SBQ performed better than ESS, SACS, and BQ in predicting OSA in patients with COPD.Keywords: Berlin questionnaire, STOP-BANG questionnairehttps://www.dovepress.com/the-screening-value-of-ess-sacs-bq-and-sbq-on-obstructive-sleep-apnea--peer-reviewed-article-COPDchronic obstructive pulmonary diseaseobstructive sleep apneareceiver-operating characteristic curveepworth sleepiness scalesleep apnea clinical scoreberlin questionnairestop-bang questionnaire. |
| spellingShingle | Xiong M Hu W Dong M Wang M Chen J Xiong H Zhong M Jiang Y Liu D Hu K The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease International Journal of COPD chronic obstructive pulmonary disease obstructive sleep apnea receiver-operating characteristic curve epworth sleepiness scale sleep apnea clinical score berlin questionnaire stop-bang questionnaire. |
| title | The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease |
| title_full | The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease |
| title_fullStr | The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease |
| title_short | The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease |
| title_sort | screening value of ess sacs bq and sbq on obstructive sleep apnea in patients with chronic obstructive pulmonary disease |
| topic | chronic obstructive pulmonary disease obstructive sleep apnea receiver-operating characteristic curve epworth sleepiness scale sleep apnea clinical score berlin questionnaire stop-bang questionnaire. |
| url | https://www.dovepress.com/the-screening-value-of-ess-sacs-bq-and-sbq-on-obstructive-sleep-apnea--peer-reviewed-article-COPD |
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