Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association Analyses

Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association Analyses

Asthma, hay fever and eczema are three comorbid diseases with high prevalence and heritability. Their common genetic architectures have not been well-elucidated. In this study, we first conducted a linkage disequilibrium score regression analysis to confirm the strong genetic correlations between as...

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Bibliographic Details
Main Authors: Hongping Guo, Jiyuan An, Zuguo Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
asthma
hay fever
eczema
association studies
shared genes
multi-trait
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00270/full

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