Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review
The aim of this review was to provide an updated overview of studies on the medical-biological activities of <i>Cinnamomum osmophloeum</i> (<i>C. osmophloeum</i>) in vitro and in vivo and the potential therapeutic use of natural agents prepared from this plant for the allevia...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/8/1/3 |
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| author | Abu Bakar Pin-Chuan Yao Valendriyani Ningrum Cheng-Tzu Liu Shih-Chieh Lee |
| author_facet | Abu Bakar Pin-Chuan Yao Valendriyani Ningrum Cheng-Tzu Liu Shih-Chieh Lee |
| author_sort | Abu Bakar |
| collection | DOAJ |
| description | The aim of this review was to provide an updated overview of studies on the medical-biological activities of <i>Cinnamomum osmophloeum</i> (<i>C. osmophloeum</i>) in vitro and in vivo and the potential therapeutic use of natural agents prepared from this plant for the alleviation of oral mucositis (OM). Reported articles were collected using web search engine tools. The systematic review was organized according to the preferred reporting items for reviews and meta-analyses (PRISMA) statement. Additional sources were identified through cross-referencing to identify the potential use of <i>C. osmophloeum</i> in the alleviation of OM. The results disclosed that <i>C. osmophloeum</i> is comprised of bioactive ingredients that could act diversely as a reagent in anti-inflammation, antibacterial, antioxidant, anti-hyperglycemic, antidyslipidemia, anti-cancer, renal disease therapy and anti-hyperuricemia capacities. Recent studies revealed that the overall effects on anti-inflammation, wound repair, and the antibacterial and antioxidant activities of its constituents would act as a potential remedy for oral mucositis. Up-to-date in vitro and in vivo studies on the medical-biological activities of <i>C. osmophloeum</i> suggested that <i>C. osmophloeum</i> and its constituents could be promising remedies as adjuvants in OM therapy and warrant further investigation. |
| first_indexed | 2024-04-14T06:49:00Z |
| format | Article |
| id | doaj.art-eeb9f56e52f84b569943f66f6560928d |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-04-14T06:49:00Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-eeb9f56e52f84b569943f66f6560928d2022-12-22T02:07:05ZengMDPI AGBiomedicines2227-90592020-01-0181310.3390/biomedicines8010003biomedicines8010003Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic ReviewAbu Bakar0Pin-Chuan Yao1Valendriyani Ningrum2Cheng-Tzu Liu3Shih-Chieh Lee4PhD Program of Biotechnology and Industry, Da-Yeh University, Dacun, Changhua 51591, TaiwanDepartment of Material Science and Engineering, Da-Yeh University, Dacun, Changhua 51591, TaiwanSchool of Dentistry, Baiturrahmah University, Kuranji, Padang 25155, IndonesiaSchool of Nutrition, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Food Science and Biotechnology, Da-Yeh University, Dacun, Changhua 51591, TaiwanThe aim of this review was to provide an updated overview of studies on the medical-biological activities of <i>Cinnamomum osmophloeum</i> (<i>C. osmophloeum</i>) in vitro and in vivo and the potential therapeutic use of natural agents prepared from this plant for the alleviation of oral mucositis (OM). Reported articles were collected using web search engine tools. The systematic review was organized according to the preferred reporting items for reviews and meta-analyses (PRISMA) statement. Additional sources were identified through cross-referencing to identify the potential use of <i>C. osmophloeum</i> in the alleviation of OM. The results disclosed that <i>C. osmophloeum</i> is comprised of bioactive ingredients that could act diversely as a reagent in anti-inflammation, antibacterial, antioxidant, anti-hyperglycemic, antidyslipidemia, anti-cancer, renal disease therapy and anti-hyperuricemia capacities. Recent studies revealed that the overall effects on anti-inflammation, wound repair, and the antibacterial and antioxidant activities of its constituents would act as a potential remedy for oral mucositis. Up-to-date in vitro and in vivo studies on the medical-biological activities of <i>C. osmophloeum</i> suggested that <i>C. osmophloeum</i> and its constituents could be promising remedies as adjuvants in OM therapy and warrant further investigation.https://www.mdpi.com/2227-9059/8/1/3<i>c. osmophloeum</i>biological activitiesoral mucositiscinnamaldehydelinalool |
| spellingShingle | Abu Bakar Pin-Chuan Yao Valendriyani Ningrum Cheng-Tzu Liu Shih-Chieh Lee Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review Biomedicines <i>c. osmophloeum</i> biological activities oral mucositis cinnamaldehyde linalool |
| title | Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review |
| title_full | Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review |
| title_fullStr | Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review |
| title_full_unstemmed | Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review |
| title_short | Beneficial Biological Activities of <i>Cinnamomum osmophloeum</i> and Its Potential Use in the Alleviation of Oral Mucositis: A Systematic Review |
| title_sort | beneficial biological activities of i cinnamomum osmophloeum i and its potential use in the alleviation of oral mucositis a systematic review |
| topic | <i>c. osmophloeum</i> biological activities oral mucositis cinnamaldehyde linalool |
| url | https://www.mdpi.com/2227-9059/8/1/3 |
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