Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report

Steroid cell tumor not otherwise specified (SCT-NOS) is a rare type of sex cord-stromal tumor with malignant potential. A 19-year-old woman underwent laparoscopic bilateral cystectomy, and postoperative pathology showed bilateral ovarian SCT-NOS. She had recurrence of the right tumor 8 years after t...

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Main Authors: Yuan Xu, Hong-Kai Shang
Format: Article
Language:English
Published: SAGE Publishing 2023-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605231194509
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author Yuan Xu
Hong-Kai Shang
author_facet Yuan Xu
Hong-Kai Shang
author_sort Yuan Xu
collection DOAJ
description Steroid cell tumor not otherwise specified (SCT-NOS) is a rare type of sex cord-stromal tumor with malignant potential. A 19-year-old woman underwent laparoscopic bilateral cystectomy, and postoperative pathology showed bilateral ovarian SCT-NOS. She had recurrence of the right tumor 8 years after the surgery, with shortened menstrual cycles, elevated testosterone and prolactin concentrations, and impaired glucose metabolism. We performed a laparoscopic right salpingo-oophorectomy. Testosterone and prolactin concentrations rapidly decreased and returned to the normal range after surgery. Subsequently, she had regular menstrual cycles and good glycemic control. The findings in our case suggest that there is a possibility of late recurrence in SCT-NOS. Therefore, we suggest that the postoperative follow-up period should be 10 years for this condition.
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spelling doaj.art-eeba8f3fd92f469ab3dc5fc6ee4dd24b2023-09-06T09:03:39ZengSAGE PublishingJournal of International Medical Research1473-23002023-09-015110.1177/03000605231194509Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case reportYuan XuHong-Kai ShangSteroid cell tumor not otherwise specified (SCT-NOS) is a rare type of sex cord-stromal tumor with malignant potential. A 19-year-old woman underwent laparoscopic bilateral cystectomy, and postoperative pathology showed bilateral ovarian SCT-NOS. She had recurrence of the right tumor 8 years after the surgery, with shortened menstrual cycles, elevated testosterone and prolactin concentrations, and impaired glucose metabolism. We performed a laparoscopic right salpingo-oophorectomy. Testosterone and prolactin concentrations rapidly decreased and returned to the normal range after surgery. Subsequently, she had regular menstrual cycles and good glycemic control. The findings in our case suggest that there is a possibility of late recurrence in SCT-NOS. Therefore, we suggest that the postoperative follow-up period should be 10 years for this condition.https://doi.org/10.1177/03000605231194509
spellingShingle Yuan Xu
Hong-Kai Shang
Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
Journal of International Medical Research
title Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
title_full Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
title_fullStr Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
title_full_unstemmed Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
title_short Recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism: a case report
title_sort recurrent steroid cell tumor not otherwise specified with elevated testosterone and prolactin concentrations and impaired glucose metabolism a case report
url https://doi.org/10.1177/03000605231194509
work_keys_str_mv AT yuanxu recurrentsteroidcelltumornototherwisespecifiedwithelevatedtestosteroneandprolactinconcentrationsandimpairedglucosemetabolismacasereport
AT hongkaishang recurrentsteroidcelltumornototherwisespecifiedwithelevatedtestosteroneandprolactinconcentrationsandimpairedglucosemetabolismacasereport