Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome
Adipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.881684/full |
| _version_ | 1811256487778975744 |
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| author | Peipei Chen Rui Jia Yuanyuan Liu Mingya Cao Liang Zhou Zhiming Zhao |
| author_facet | Peipei Chen Rui Jia Yuanyuan Liu Mingya Cao Liang Zhou Zhiming Zhao |
| author_sort | Peipei Chen |
| collection | DOAJ |
| description | Adipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in many pathophysiological processes, such as energy metabolism regulation, glucose and lipid metabolism, and inflammation. Polycystic ovary syndrome (PCOS) is a disorder that mainly involves the female reproductive system, affecting women of childbearing age particularly. Insulin resistance (IR) and hyperandrogenemia (HA) have been implicated as a critical link involving the etiology and outcome of PCOS. A great deal of studies has bridged the gap between adipokines (such as Adiponectin, Chemerin, Metrnl, Apelin, Resistin, Visfatin, Leptin, Vaspin, Lipocalin 2, and Omentin) and reproductive fitness. In this review, we will focus on the adipokines’ functions on PCOS and come up with some points of view on the basis of current research. |
| first_indexed | 2024-04-12T17:40:57Z |
| format | Article |
| id | doaj.art-eec07a1f74e84a0f9151b121b360996e |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-12T17:40:57Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-eec07a1f74e84a0f9151b121b360996e2022-12-22T03:22:48ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-05-011310.3389/fendo.2022.881684881684Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary SyndromePeipei ChenRui JiaYuanyuan LiuMingya CaoLiang ZhouZhiming ZhaoAdipose tissue, one type of loose connective tissue in the human body, maintains the primary task of energy storage. Adipose tissue is not only an energy reservoir but also plays a vital role as the largest endocrine organ of the whole body via releasing a variety of adipokines, which participate in many pathophysiological processes, such as energy metabolism regulation, glucose and lipid metabolism, and inflammation. Polycystic ovary syndrome (PCOS) is a disorder that mainly involves the female reproductive system, affecting women of childbearing age particularly. Insulin resistance (IR) and hyperandrogenemia (HA) have been implicated as a critical link involving the etiology and outcome of PCOS. A great deal of studies has bridged the gap between adipokines (such as Adiponectin, Chemerin, Metrnl, Apelin, Resistin, Visfatin, Leptin, Vaspin, Lipocalin 2, and Omentin) and reproductive fitness. In this review, we will focus on the adipokines’ functions on PCOS and come up with some points of view on the basis of current research.https://www.frontiersin.org/articles/10.3389/fendo.2022.881684/fullPCOSadipokinesfemale reproductive systemreproductive endocrinologyinsulin resistance |
| spellingShingle | Peipei Chen Rui Jia Yuanyuan Liu Mingya Cao Liang Zhou Zhiming Zhao Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome Frontiers in Endocrinology PCOS adipokines female reproductive system reproductive endocrinology insulin resistance |
| title | Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome |
| title_full | Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome |
| title_fullStr | Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome |
| title_full_unstemmed | Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome |
| title_short | Progress of Adipokines in the Female Reproductive System: A Focus on Polycystic Ovary Syndrome |
| title_sort | progress of adipokines in the female reproductive system a focus on polycystic ovary syndrome |
| topic | PCOS adipokines female reproductive system reproductive endocrinology insulin resistance |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.881684/full |
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