LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis

LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis

In healthy arteries, expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is almost undetectable. However, in proatherogenic conditions, LOX-1 is markedly up-regulated in vascular cells. In atherosclerosis, LOX-1 appears to be the key scavenger receptor for binding oxidized...

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Bibliographic Details
Main Authors: Dimitry A. Chistiakov, Alexander N. Orekhov, Yuri V. Bobryshev
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Atherosclerosis
Atherogenesis
Arteries
Lectin-like oxidized low-density lipoprotein receptor-1
LOX-1
Oxidized LDL
OxLDL
Online Access:http://www.karger.com/Article/FullText/443123

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