Bioactive Phenolic Amides from Celtis africana
Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their st...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-03-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/3/2675/ |
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| author | Nighat Afza Lubna Iqbal Abdul Malik Ghada Ahmed Fawzy Azza Muhammed El-Shafae Shagufta Perveen Areej Mohammad Al-Taweel Mehreen Latif |
| author_facet | Nighat Afza Lubna Iqbal Abdul Malik Ghada Ahmed Fawzy Azza Muhammed El-Shafae Shagufta Perveen Areej Mohammad Al-Taweel Mehreen Latif |
| author_sort | Nighat Afza |
| collection | DOAJ |
| description | Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity. |
| first_indexed | 2024-12-23T14:58:15Z |
| format | Article |
| id | doaj.art-eec25e732cb7492fa84a2972f8b0d8bb |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T14:58:15Z |
| publishDate | 2012-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-eec25e732cb7492fa84a2972f8b0d8bb2022-12-21T17:42:43ZengMDPI AGMolecules1420-30492012-03-011732675268210.3390/molecules17032675Bioactive Phenolic Amides from Celtis africanaNighat AfzaLubna IqbalAbdul MalikGhada Ahmed FawzyAzza Muhammed El-ShafaeShagufta PerveenAreej Mohammad Al-TaweelMehreen LatifNine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.http://www.mdpi.com/1420-3049/17/3/2675/Celtis africanaantioxidantanti-inflammatoryacetylcholinestrease enzyme inhibition |
| spellingShingle | Nighat Afza Lubna Iqbal Abdul Malik Ghada Ahmed Fawzy Azza Muhammed El-Shafae Shagufta Perveen Areej Mohammad Al-Taweel Mehreen Latif Bioactive Phenolic Amides from Celtis africana Molecules Celtis africana antioxidant anti-inflammatory acetylcholinestrease enzyme inhibition |
| title | Bioactive Phenolic Amides from Celtis africana |
| title_full | Bioactive Phenolic Amides from Celtis africana |
| title_fullStr | Bioactive Phenolic Amides from Celtis africana |
| title_full_unstemmed | Bioactive Phenolic Amides from Celtis africana |
| title_short | Bioactive Phenolic Amides from Celtis africana |
| title_sort | bioactive phenolic amides from celtis africana |
| topic | Celtis africana antioxidant anti-inflammatory acetylcholinestrease enzyme inhibition |
| url | http://www.mdpi.com/1420-3049/17/3/2675/ |
| work_keys_str_mv | AT nighatafza bioactivephenolicamidesfromceltisafricana AT lubnaiqbal bioactivephenolicamidesfromceltisafricana AT abdulmalik bioactivephenolicamidesfromceltisafricana AT ghadaahmedfawzy bioactivephenolicamidesfromceltisafricana AT azzamuhammedelshafae bioactivephenolicamidesfromceltisafricana AT shaguftaperveen bioactivephenolicamidesfromceltisafricana AT areejmohammadaltaweel bioactivephenolicamidesfromceltisafricana AT mehreenlatif bioactivephenolicamidesfromceltisafricana |