cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.

Human cytomegalovirus (HCMV) infections of healthy individuals are mostly unnoticed and result in viral latency. However, HCMV can also cause devastating disease, e.g., upon reactivation in immunocompromised patients. Yet, little is known about human immune cell sensing of DNA-encoded HCMV. Recent s...

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Bibliographic Details
Main Authors:	Jennifer Paijo, Marius Döring, Julia Spanier, Elena Grabski, Mohammed Nooruzzaman, Tobias Schmidt, Gregor Witte, Martin Messerle, Veit Hornung, Volkhard Kaever, Ulrich Kalinke
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-04-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1005546

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