Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves
ABSTRACT: The role of colostrum management in providing adequate immunological protection to neonatal calves has been widely investigated, and thresholds for colostrum quality, as well as optimum volume and timing for colostrum feeding have been established. However, limited information is available...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Journal of Dairy Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022030221009899 |
| _version_ | 1828318989598588928 |
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| author | J. Barry E.A.M. Bokkers R. Sayers J.P. Murphy I.J.M. de Boer E. Kennedy |
| author_facet | J. Barry E.A.M. Bokkers R. Sayers J.P. Murphy I.J.M. de Boer E. Kennedy |
| author_sort | J. Barry |
| collection | DOAJ |
| description | ABSTRACT: The role of colostrum management in providing adequate immunological protection to neonatal calves has been widely investigated, and thresholds for colostrum quality, as well as optimum volume and timing for colostrum feeding have been established. However, limited information is available on the effect of colostrum source (single dam or pooled) on passive immunity, as well as subsequent antibody survival in the calf. This study aimed to assess the effect of feeding single-dam colostrum (own and other dam) or pooled colostrum on transfer of passive immunity, and also investigate the rate of depletion of disease-specific antibodies among dairy calves. In total, 320 cows and 119 dairy heifer calves were enrolled in the study. Calves were blood-sampled immediately after birth and received either own-dam, other-dam, or pooled colostrum. Calves were blood-sampled at 24 h to assess serum IgG concentrations and at monthly intervals thereafter to document disease-specific antibody survival. Mean colostrum IgG concentration was higher for other-dam treatment group, whereas own-dam and pooled treatments were similar. For all treatment groups, the mean IgG concentration was >80 mg/mL, exceeding the quality threshold of 50 mg/mL. Mean calf serum IgG concentration was lower for calves fed pooled colostrum compared with those that received colostrum from a single cow. There was a negative association with 24-h serum IgG and calf birth bodyweight; calves <30 kg at birth had the highest 24-h serum IgG concentration. Survival of antibodies to bovine viral diarrhea, Salmonella infection, leptospirosis, bovine parainfluenza 3 virus, bovine respiratory syncytical virus, rotavirus, and coronavirus was not associated with colostrum source; however, antibodies to infectious bovine rhinotracheitis had a greater period of survival among calves fed own-dam colostrum. We found that feeding single-dam colostrum can thus improve calf immunity through increased serum IgG levels and antibody survival rates. Furthermore, we hypothesize that immune exclusion may occur with pooled colostrum; therefore, providing pooled colostrum may still be a good practice as long as it can be ensured that enough antibodies are absorbed into the blood stream to deal with pathogens calves may encounter because different dams may have antibodies against different strains of viruses and bacteria, yielding cross protection. |
| first_indexed | 2024-04-13T17:51:01Z |
| format | Article |
| id | doaj.art-eece03759cf043ab8518d8c2c2505bf3 |
| institution | Directory Open Access Journal |
| issn | 0022-0302 |
| language | English |
| last_indexed | 2024-04-13T17:51:01Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Dairy Science |
| spelling | doaj.art-eece03759cf043ab8518d8c2c2505bf32022-12-22T02:36:44ZengElsevierJournal of Dairy Science0022-03022022-01-011051560571Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calvesJ. Barry0E.A.M. Bokkers1R. Sayers2J.P. Murphy3I.J.M. de Boer4E. Kennedy5Teagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, P61 C996 Ireland; Animal Production Systems group, Wageningen University & Research, PO Box 338, 6700 AH Wageningen, the NetherlandsAnimal Production Systems group, Wageningen University & Research, PO Box 338, 6700 AH Wageningen, the NetherlandsTeagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, P61 C996 IrelandTeagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, P61 C996 IrelandAnimal Production Systems group, Wageningen University & Research, PO Box 338, 6700 AH Wageningen, the NetherlandsTeagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, P61 C996 Ireland; Corresponding authorABSTRACT: The role of colostrum management in providing adequate immunological protection to neonatal calves has been widely investigated, and thresholds for colostrum quality, as well as optimum volume and timing for colostrum feeding have been established. However, limited information is available on the effect of colostrum source (single dam or pooled) on passive immunity, as well as subsequent antibody survival in the calf. This study aimed to assess the effect of feeding single-dam colostrum (own and other dam) or pooled colostrum on transfer of passive immunity, and also investigate the rate of depletion of disease-specific antibodies among dairy calves. In total, 320 cows and 119 dairy heifer calves were enrolled in the study. Calves were blood-sampled immediately after birth and received either own-dam, other-dam, or pooled colostrum. Calves were blood-sampled at 24 h to assess serum IgG concentrations and at monthly intervals thereafter to document disease-specific antibody survival. Mean colostrum IgG concentration was higher for other-dam treatment group, whereas own-dam and pooled treatments were similar. For all treatment groups, the mean IgG concentration was >80 mg/mL, exceeding the quality threshold of 50 mg/mL. Mean calf serum IgG concentration was lower for calves fed pooled colostrum compared with those that received colostrum from a single cow. There was a negative association with 24-h serum IgG and calf birth bodyweight; calves <30 kg at birth had the highest 24-h serum IgG concentration. Survival of antibodies to bovine viral diarrhea, Salmonella infection, leptospirosis, bovine parainfluenza 3 virus, bovine respiratory syncytical virus, rotavirus, and coronavirus was not associated with colostrum source; however, antibodies to infectious bovine rhinotracheitis had a greater period of survival among calves fed own-dam colostrum. We found that feeding single-dam colostrum can thus improve calf immunity through increased serum IgG levels and antibody survival rates. Furthermore, we hypothesize that immune exclusion may occur with pooled colostrum; therefore, providing pooled colostrum may still be a good practice as long as it can be ensured that enough antibodies are absorbed into the blood stream to deal with pathogens calves may encounter because different dams may have antibodies against different strains of viruses and bacteria, yielding cross protection.http://www.sciencedirect.com/science/article/pii/S0022030221009899survivalhealthimmunoglobulinheiferbirthweight |
| spellingShingle | J. Barry E.A.M. Bokkers R. Sayers J.P. Murphy I.J.M. de Boer E. Kennedy Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves Journal of Dairy Science survival health immunoglobulin heifer birthweight |
| title | Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves |
| title_full | Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves |
| title_fullStr | Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves |
| title_full_unstemmed | Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves |
| title_short | Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves |
| title_sort | effect of feeding single dam or pooled colostrum on maternally derived immunity in dairy calves |
| topic | survival health immunoglobulin heifer birthweight |
| url | http://www.sciencedirect.com/science/article/pii/S0022030221009899 |
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