Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005
Approximately 179 million cases of acute gastroenteritis (AGE) occur annually in the United States. However, lack of routine clinical testing for viruses limits understanding of their role among persons seeking medical care. Fecal specimens submitted for routine bacterial culture through a health ma...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2011-08-01
|
| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/17/8/10-1533_article |
| _version_ | 1819126795779178496 |
|---|---|
| author | Aron J. Hall Mariana Rosenthal Nicole Gregoricus Sharon A. Greene Jeana Ferguson Olga L. Henao Jan Vinjé Ben A. Lopman Umesh D. Parashar Marc-Alain Widdowson |
| author_facet | Aron J. Hall Mariana Rosenthal Nicole Gregoricus Sharon A. Greene Jeana Ferguson Olga L. Henao Jan Vinjé Ben A. Lopman Umesh D. Parashar Marc-Alain Widdowson |
| author_sort | Aron J. Hall |
| collection | DOAJ |
| description | Approximately 179 million cases of acute gastroenteritis (AGE) occur annually in the United States. However, lack of routine clinical testing for viruses limits understanding of their role among persons seeking medical care. Fecal specimens submitted for routine bacterial culture through a health maintenance organization in Georgia, USA, were tested with molecular diagnostic assays for norovirus, rotavirus, astrovirus, sapovirus, and adenovirus. Incidence was estimated by using national health care utilization rates. Routine clinical diagnostics identified a pathogen in 42 (7.3%) of 572 specimens; inclusion of molecular viral testing increased pathogen detection to 15.7%. Community AGE incidence was 41,000 cases/100,000 person-years and outpatient incidence was 5,400/100,000 person-years. Norovirus was the most common pathogen, accounting for 6,500 (16%) and 640 (12%) per 100,000 person-years of community and outpatient AGE episodes, respectively. This study demonstrates that noroviruses are leading causes of AGE among persons seeking medical care. |
| first_indexed | 2024-12-22T08:01:43Z |
| format | Article |
| id | doaj.art-eed0c34b20244dc6b0fceb9ac899a4be |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-22T08:01:43Z |
| publishDate | 2011-08-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-eed0c34b20244dc6b0fceb9ac899a4be2022-12-21T18:33:15ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592011-08-011781381138810.3201/eid1708.101533Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005Aron J. HallMariana RosenthalNicole GregoricusSharon A. GreeneJeana FergusonOlga L. HenaoJan VinjéBen A. LopmanUmesh D. ParasharMarc-Alain WiddowsonApproximately 179 million cases of acute gastroenteritis (AGE) occur annually in the United States. However, lack of routine clinical testing for viruses limits understanding of their role among persons seeking medical care. Fecal specimens submitted for routine bacterial culture through a health maintenance organization in Georgia, USA, were tested with molecular diagnostic assays for norovirus, rotavirus, astrovirus, sapovirus, and adenovirus. Incidence was estimated by using national health care utilization rates. Routine clinical diagnostics identified a pathogen in 42 (7.3%) of 572 specimens; inclusion of molecular viral testing increased pathogen detection to 15.7%. Community AGE incidence was 41,000 cases/100,000 person-years and outpatient incidence was 5,400/100,000 person-years. Norovirus was the most common pathogen, accounting for 6,500 (16%) and 640 (12%) per 100,000 person-years of community and outpatient AGE episodes, respectively. This study demonstrates that noroviruses are leading causes of AGE among persons seeking medical care.https://wwwnc.cdc.gov/eid/article/17/8/10-1533_articlenorovirusvirusesgastroenteritisAGEetiologyincidence |
| spellingShingle | Aron J. Hall Mariana Rosenthal Nicole Gregoricus Sharon A. Greene Jeana Ferguson Olga L. Henao Jan Vinjé Ben A. Lopman Umesh D. Parashar Marc-Alain Widdowson Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 Emerging Infectious Diseases norovirus viruses gastroenteritis AGE etiology incidence |
| title | Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 |
| title_full | Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 |
| title_fullStr | Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 |
| title_full_unstemmed | Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 |
| title_short | Incidence of Acute Gastroenteritis and Role of Norovirus, Georgia, USA, 2004–2005 |
| title_sort | incidence of acute gastroenteritis and role of norovirus georgia usa 2004 2005 |
| topic | norovirus viruses gastroenteritis AGE etiology incidence |
| url | https://wwwnc.cdc.gov/eid/article/17/8/10-1533_article |
| work_keys_str_mv | AT aronjhall incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT marianarosenthal incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT nicolegregoricus incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT sharonagreene incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT jeanaferguson incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT olgalhenao incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT janvinje incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT benalopman incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT umeshdparashar incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 AT marcalainwiddowson incidenceofacutegastroenteritisandroleofnorovirusgeorgiausa20042005 |