Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission.

Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission.

Efavirenz-based first-line regimens have been widely used for children ≥3 years of age starting antiretroviral therapy, despite possible resistance with prior exposure to non-nucleoside reverse transcriptase inhibitors for prevention of mother-to-child transmission (PMTCT). We used logistic regressi...

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Bibliographic Details
Main Authors: Patience Nyakato, Mary-Ann Davies, Karl-Gunter Technau, Geoffrey Fatti, Helena Rabie, Frank Tanser, Andrew Boulle, Robin Wood, Brian Eley, Shobna Sawry, Janet Giddy, Nosisa Sipambo, Louise Kuhn, Lee Fairlie, International epidemiology Database to Evaluate AIDS-Southern Africa (IeDEA-SA) Collaboration
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233693

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