δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats

δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats

PnTx4(6-1), henceforth renamed δ-Ctenitoxin-Pn1a (δ-CNTX-Pn1a), a peptide from Phoneutria nigriventer spider venom, initially described as an insect toxin, binds to site 3 of sodium channels in nerve cord synaptosomes and slows down sodium current inactivation in isolated axons in cockroaches (Perip...

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Bibliographic Details
Main Authors:	Bruna Luiza Emerich, Renata C. M. Ferreira, Marta N. Cordeiro, Márcia Helena Borges, Adriano M. C. Pimenta, Suely G. Figueiredo, Igor Dimitri G. Duarte, Maria Elena de Lima
Format:	Article
Language:	English
Published:	MDPI AG 2016-04-01
Series:	Toxins
Subjects:	spider toxin δ-Ctenitoxin-Pn1a PnTx4(6-1) Phoneutria nigriventer spider venom antinociception
Online Access:	http://www.mdpi.com/2072-6651/8/4/106

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