New Findings: Hindlimb Unloading Causes Nucleocytoplasmic Ca<sup>2+</sup> Overload and DNA Damage in Skeletal Muscle

New Findings: Hindlimb Unloading Causes Nucleocytoplasmic Ca<sup>2+</sup> Overload and DNA Damage in Skeletal Muscle

Disuse atrophy of skeletal muscle is associated with a severe imbalance in cellular Ca<sup>2+</sup> homeostasis and marked increase in nuclear apoptosis. Nuclear Ca<sup>2+</sup> is involved in the regulation of cellular Ca<sup>2+</sup> homeostasis. However, it rem...

Full description

Bibliographic Details
Main Authors: Huajian Yang, Huiping Wang, Fangyang Pan, Yuxi Guo, Liqi Cao, Wenjing Yan, Yunfang Gao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
skeletal muscle
hindlimb unloading
nuclear Ca<sup>2+</sup> regulation
nuclear apoptosis
Online Access:https://www.mdpi.com/2073-4409/12/7/1077

Similar Items

Similar Items