Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation
Objective: To assist clinicians to operate repetitive Transcranial Magnetic Stimulation (rTMS) precisely based on the coil magnetic field spatial distribution with Magnetic Resonance Imaging (MRI) Navigation.Methods: A fast method for calculating electromagnetic fields in layered brain structures in...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-08-01
|
| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2019.00858/full |
| _version_ | 1818601031900069888 |
|---|---|
| author | Shijun Li Shijun Li Yi Wang ShengJie Li Yanwei Lv Lei Zhang Jun Zou Lin Ma |
| author_facet | Shijun Li Shijun Li Yi Wang ShengJie Li Yanwei Lv Lei Zhang Jun Zou Lin Ma |
| author_sort | Shijun Li |
| collection | DOAJ |
| description | Objective: To assist clinicians to operate repetitive Transcranial Magnetic Stimulation (rTMS) precisely based on the coil magnetic field spatial distribution with Magnetic Resonance Imaging (MRI) Navigation.Methods: A fast method for calculating electromagnetic fields in layered brain structures in frequency domain was proposed. By approaching Bessel function in different intervals, the integral with a highly oscillatory kernel was transformed into two parts: a definite integral and a weakened oscillatory one. The distribution of induced current density and magnetic field intensity of rTMS stimulation effect on brain was quantitatively calculated, so that clinicians could intuitively grasp the safe range of coil stimulation on the brain. Then, the crucial factor of the stimulation effect of rTMS was determined, and an accurate coil positioning of the rTMS efficiently was completed.Result: The maximal attenuation of induced electric field and magnetic induction intensity was 72.20 and 86.867% at 3 cm away from the skin in the brain layered model. The clinical examination results of electric field intensity distribution, magnetic field intensity distribution, current density distribution, layered brain modeling, and coil location speed in the brain model teaching group were significantly higher than those in the traditional teaching group (P < 0.001).Conclusion: It is suitable for clinicians to quickly complete the precise positioning of rTMS, master the adjustment of coil stimulation therapeutic parameters, and realize the precise positioning operation of rTMS with MRI navigation in intracranial.Clinical Trial registration: Chinese Clinical Trial Registry (ChiCTR1800018616); Registered on 30th September 2018 |
| first_indexed | 2024-12-16T12:44:55Z |
| format | Article |
| id | doaj.art-eedfe6983da54ae7b5efb3faab9ed328 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-16T12:44:55Z |
| publishDate | 2019-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-eedfe6983da54ae7b5efb3faab9ed3282022-12-21T22:31:19ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2019-08-011310.3389/fnins.2019.00858464182Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging NavigationShijun Li0Shijun Li1Yi Wang2ShengJie Li3Yanwei Lv4Lei Zhang5Jun Zou6Lin Ma7Department of Medical Instruments, Chinese People's Liberation Army General Hospital, Beijing, ChinaDepartment of Radiology, Chinese People's Liberation Army General Hospital, Beijing, ChinaDepartment of Stomatology, Chinese People's Liberation Army General Hospital, Beijing, ChinaDepartment of Rehabilitation, Chinese People's Liberation Army General Hospital, Beijing, ChinaClinical Epidemiology and Biostatistics Research Office, Beijing Research Institute of Traumatology and Orthopaedics, Beijing, ChinaDepartment of Medical Information, Chinese People's Liberation Army General Hospital, Beijing, ChinaDepartment of Electrical Engineering, Tsinghua University, Beijing, ChinaDepartment of Radiology, Chinese People's Liberation Army General Hospital, Beijing, ChinaObjective: To assist clinicians to operate repetitive Transcranial Magnetic Stimulation (rTMS) precisely based on the coil magnetic field spatial distribution with Magnetic Resonance Imaging (MRI) Navigation.Methods: A fast method for calculating electromagnetic fields in layered brain structures in frequency domain was proposed. By approaching Bessel function in different intervals, the integral with a highly oscillatory kernel was transformed into two parts: a definite integral and a weakened oscillatory one. The distribution of induced current density and magnetic field intensity of rTMS stimulation effect on brain was quantitatively calculated, so that clinicians could intuitively grasp the safe range of coil stimulation on the brain. Then, the crucial factor of the stimulation effect of rTMS was determined, and an accurate coil positioning of the rTMS efficiently was completed.Result: The maximal attenuation of induced electric field and magnetic induction intensity was 72.20 and 86.867% at 3 cm away from the skin in the brain layered model. The clinical examination results of electric field intensity distribution, magnetic field intensity distribution, current density distribution, layered brain modeling, and coil location speed in the brain model teaching group were significantly higher than those in the traditional teaching group (P < 0.001).Conclusion: It is suitable for clinicians to quickly complete the precise positioning of rTMS, master the adjustment of coil stimulation therapeutic parameters, and realize the precise positioning operation of rTMS with MRI navigation in intracranial.Clinical Trial registration: Chinese Clinical Trial Registry (ChiCTR1800018616); Registered on 30th September 2018https://www.frontiersin.org/article/10.3389/fnins.2019.00858/fullrTMS (repetitive transcranial magnetic stimulation)induced electric fieldbrain modelingclinical teaching methodologymagnetic resonance imaging navigation |
| spellingShingle | Shijun Li Shijun Li Yi Wang ShengJie Li Yanwei Lv Lei Zhang Jun Zou Lin Ma Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation Frontiers in Neuroscience rTMS (repetitive transcranial magnetic stimulation) induced electric field brain modeling clinical teaching methodology magnetic resonance imaging navigation |
| title | Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation |
| title_full | Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation |
| title_fullStr | Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation |
| title_full_unstemmed | Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation |
| title_short | Research on Assisting Clinicians to Operate rTMS Precisely Based on the Coil Magnetic Field Spatial Distribution With Magnetic Resonance Imaging Navigation |
| title_sort | research on assisting clinicians to operate rtms precisely based on the coil magnetic field spatial distribution with magnetic resonance imaging navigation |
| topic | rTMS (repetitive transcranial magnetic stimulation) induced electric field brain modeling clinical teaching methodology magnetic resonance imaging navigation |
| url | https://www.frontiersin.org/article/10.3389/fnins.2019.00858/full |
| work_keys_str_mv | AT shijunli researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT shijunli researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT yiwang researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT shengjieli researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT yanweilv researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT leizhang researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT junzou researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation AT linma researchonassistingclinicianstooperatertmspreciselybasedonthecoilmagneticfieldspatialdistributionwithmagneticresonanceimagingnavigation |