Mental pain and suicide risk: implications for neuroimaging

Abstract Campaigns have been launched to make sense of what makes a specific individual suicidal. We know that suicidal individuals give definite warning signs, mainly from their ambivalence about ending their own lives. Classical suicidology posited that the suicidal individual experiences unbear...

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Main Author: M. Pompili
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823001372/type/journal_article
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author M. Pompili
author_facet M. Pompili
author_sort M. Pompili
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description Abstract Campaigns have been launched to make sense of what makes a specific individual suicidal. We know that suicidal individuals give definite warning signs, mainly from their ambivalence about ending their own lives. Classical suicidology posited that the suicidal individual experiences unbearable psychological pain (psychache) or suffering and that suicide might be, at least in part, an attempt to escape from this suffering, emphasizing that suicide is not a movement toward death but rather an escape from unbearable emotion and unendurable or unacceptable anguish. Suicide occurs when that individual deems the psychache to be unbearable. Neuroimaging studies demonstrated that such emotional pain shares the same neuroanatomical circuit of somatic pain. Furthermore, concepts related to death, failure, or other unfortunate circumstances activate specific cerebral areas in a suicidal individual compared to a non-suicidal subject. The author conducted a sizeable clinical investigation on mental pain related to psychiatric disorders and suicide risk. Implications for further research are discussed during the presentation. Disclosure of Interest M. Pompili Consultant of: Janssen, Lundbeck, Recordati, MSD, Speakers bureau of: Janssen, Lundbeck, Angelini Pharma, Pfizer
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spelling doaj.art-eee0ea4d2e9e4549b8bdbfe3e90b88ea2023-11-17T05:08:37ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S36S3610.1192/j.eurpsy.2023.137Mental pain and suicide risk: implications for neuroimagingM. Pompili0Sapienza University of Rome, Rome, Italy Abstract Campaigns have been launched to make sense of what makes a specific individual suicidal. We know that suicidal individuals give definite warning signs, mainly from their ambivalence about ending their own lives. Classical suicidology posited that the suicidal individual experiences unbearable psychological pain (psychache) or suffering and that suicide might be, at least in part, an attempt to escape from this suffering, emphasizing that suicide is not a movement toward death but rather an escape from unbearable emotion and unendurable or unacceptable anguish. Suicide occurs when that individual deems the psychache to be unbearable. Neuroimaging studies demonstrated that such emotional pain shares the same neuroanatomical circuit of somatic pain. Furthermore, concepts related to death, failure, or other unfortunate circumstances activate specific cerebral areas in a suicidal individual compared to a non-suicidal subject. The author conducted a sizeable clinical investigation on mental pain related to psychiatric disorders and suicide risk. Implications for further research are discussed during the presentation. Disclosure of Interest M. Pompili Consultant of: Janssen, Lundbeck, Recordati, MSD, Speakers bureau of: Janssen, Lundbeck, Angelini Pharma, Pfizerhttps://www.cambridge.org/core/product/identifier/S0924933823001372/type/journal_article
spellingShingle M. Pompili
Mental pain and suicide risk: implications for neuroimaging
European Psychiatry
title Mental pain and suicide risk: implications for neuroimaging
title_full Mental pain and suicide risk: implications for neuroimaging
title_fullStr Mental pain and suicide risk: implications for neuroimaging
title_full_unstemmed Mental pain and suicide risk: implications for neuroimaging
title_short Mental pain and suicide risk: implications for neuroimaging
title_sort mental pain and suicide risk implications for neuroimaging
url https://www.cambridge.org/core/product/identifier/S0924933823001372/type/journal_article
work_keys_str_mv AT mpompili mentalpainandsuicideriskimplicationsforneuroimaging