2'-Hydroxyflavanone activity in vitro and in vivo against wild-type and antimony-resistant Leishmania amazonensis.

2'-Hydroxyflavanone activity in vitro and in vivo against wild-type and antimony-resistant Leishmania amazonensis.

<h4>Background</h4>To overcome the current problems in leishmaniasis chemotherapy, natural products have become an interesting alternative over the past few decades. Flavonoids have been studied as promising family of compounds for leishmaniasis treatment. 2'-Hydroxyflavanone (2HF)...

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Bibliographic Details
Main Authors: Luiza F O Gervazoni, Gabriella Gonçalves-Ozório, Elmo E Almeida-Amaral
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006930

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