Calcium Pyrophosphate Deposition Disease in the Craniovertebral Junction: An Unusual Cause of Neck Pain
Crowned Dens Syndrome (CDS) is a rare manifestation of Calcium Pyrophosphate Deposition (CPPD) disease characterised by calcification around the odontoid process in the atlantoaxial joint. It manifests as intense neck pain with signs of systemic inflammation, including elevated acute phase reactan...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/15273/49707_CE[Ra1]_F(SL)_PF1(PS_OM)_PFA(PS_KM)_PN(KM).pdf |
| Summary: | Crowned Dens Syndrome (CDS) is a rare manifestation of Calcium Pyrophosphate Deposition (CPPD) disease characterised by
calcification around the odontoid process in the atlantoaxial joint. It manifests as intense neck pain with signs of systemic inflammation,
including elevated acute phase reactants. Thus, it can simulate other causes of neck pain and diagnosis can be challenging.
Moreover, CPPD disease can be asymptomatic and observed as radiological finding. Here in, two cases of spinal CPPD disease
with distinct presentations are reported. The first of 83-year-old woman describes CDS that was misdiagnosed as Polymyalgia
Rheumatica (PMR) whereas in the second case of 70-year-old female calcification around the odontoid process was incidentally
found in a patient with acute cervical spine fracture. These two reported cases highlight the spectrum of manifestations of spinal
CPPD disease and support the notion that careful discrimination of the cause of neck pain is essential for improving outcomes. |
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| ISSN: | 2249-782X 0973-709X |