Influence of Pelvic Intensity-Modulated Radiation Therapy With Concurrent Cisplatin-Based Chemotherapy of Cervical Cancer on the Vaginal Microbiome

Influence of Pelvic Intensity-Modulated Radiation Therapy With Concurrent Cisplatin-Based Chemotherapy of Cervical Cancer on the Vaginal Microbiome

Pelvic intensity-modulated radiation therapy (IMRT) combined with concurrent chemotherapy is an effective treatment for cervical cancer; however, radiation resistance impairs its clinical benefit. The vaginal microbiome plays an important but poorly understood role in cancer radiochemotherapy. In th...

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Bibliographic Details
Main Authors: Li Jiang, Bo Li, Yong Zhang, Shanshan Ma, Chang Liu, Feifei Liang, Zhuxin Wei, Tingting Huang, Rensheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
vaginal microbiome
cervical cancer
intensity-modulated radiation therapy
radiochemotherapy
16S rRNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.615439/full

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