Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors

Vitamin D deficiency is a worldwide condition, which has been linked to a variety of health-related issues. Vitamin D can be beneficial to cardiovascular patients and those suffering from depression and anxiety, based on Survey of Ultraviolet Intake by Nutritional Approach (SUVINA study), ,showing t...

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Main Authors: Payam Sharifan, Hamideh Ghazizadeh, Susan Darroudi, Alireza Ghodsi, Sara Saffar Soflaei, Davoud Tanbacoochi, Mohammad Reza Fazl Mashhadi, Mohammad Amin Mohammadi, Ali Ebrahimi dabagh, Sara Moazedi, Maryam Mohammadi Bajgiran, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Sciences and Health Services 2024-02-01
Series:Journal of Nutrition and Food Security
Subjects:
Online Access:http://jnfs.ssu.ac.ir/article-1-781-en.pdf
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author Payam Sharifan
Hamideh Ghazizadeh
Susan Darroudi
Alireza Ghodsi
Sara Saffar Soflaei
Davoud Tanbacoochi
Mohammad Reza Fazl Mashhadi
Mohammad Amin Mohammadi
Ali Ebrahimi dabagh
Sara Moazedi
Maryam Mohammadi Bajgiran
Gordon Ferns
Habibollah Esmaily
Majid Ghayour-Mobarhan
author_facet Payam Sharifan
Hamideh Ghazizadeh
Susan Darroudi
Alireza Ghodsi
Sara Saffar Soflaei
Davoud Tanbacoochi
Mohammad Reza Fazl Mashhadi
Mohammad Amin Mohammadi
Ali Ebrahimi dabagh
Sara Moazedi
Maryam Mohammadi Bajgiran
Gordon Ferns
Habibollah Esmaily
Majid Ghayour-Mobarhan
author_sort Payam Sharifan
collection DOAJ
description Vitamin D deficiency is a worldwide condition, which has been linked to a variety of health-related issues. Vitamin D can be beneficial to cardiovascular patients and those suffering from depression and anxiety, based on Survey of Ultraviolet Intake by Nutritional Approach (SUVINA study), ,showing the potential effects of vitamin D-fortified dairy products on anxiety, depression, and stress in subjects with cardiovascular disease (CVD) risk factors. Methods: It was a quadruple-blind randomized controlled trial. Individuals were randomly allocated to one of four groups: fortified low-fat milk (FM), non-fortified low-fat milk (NFM), fortified low-fat yogurt (FY), and non-fortified low-fat yogurt (NFY). FM and FY groups were fortified with 1500 IU nano-encapsulated vitamin D3. Anthropometric parameters as well as depression, anxiety, and stress scores were measured at baseline and after a ten-week trial in Mashhad, Iran. Results: Totally, 289 participants (143 men, 146 women) with a mean age of 41.86±7.81years were enrolled in the study. There was no statistical difference between the scores of depression, anxiety, and stress in participants with and without CVD risk factors (P>0.05).  No statistical difference was found in the subgroup analysis based on milk and yogurt consumption. Conclusions: Fortified low-fat milk containing 1,500 IU of vitamin D has no impact on improving depression, anxiety, and stress during ten weeks. However, further studies with higher vitamin D doses for a longer duration are recommended.
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spelling doaj.art-eee955d2c79c47f281aec31d808f28b92024-02-14T06:51:58ZengShahid Sadoughi University of Medical Sciences and Health ServicesJournal of Nutrition and Food Security2476-74172476-74252024-02-01916980Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk FactorsPayam Sharifan0Hamideh Ghazizadeh1Susan Darroudi2Alireza Ghodsi3Sara Saffar Soflaei4Davoud Tanbacoochi5Mohammad Reza Fazl Mashhadi6Mohammad Amin Mohammadi7Ali Ebrahimi dabagh8Sara Moazedi9Maryam Mohammadi Bajgiran10Gordon Ferns11Habibollah Esmaily12Majid Ghayour-Mobarhan13 Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 3 International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Department of Nutritions, Varastegan Institute for Medical Sciences, Mashhad, Iran Department of Nutritions, Varastegan Institute for Medical Sciences, Mashhad, Iran Department of Nutritions, Varastegan Institute for Medical Sciences, Mashhad, Iran Department of Nutritions, Varastegan Institute for Medical Sciences, Mashhad, Iran International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK; Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Vitamin D deficiency is a worldwide condition, which has been linked to a variety of health-related issues. Vitamin D can be beneficial to cardiovascular patients and those suffering from depression and anxiety, based on Survey of Ultraviolet Intake by Nutritional Approach (SUVINA study), ,showing the potential effects of vitamin D-fortified dairy products on anxiety, depression, and stress in subjects with cardiovascular disease (CVD) risk factors. Methods: It was a quadruple-blind randomized controlled trial. Individuals were randomly allocated to one of four groups: fortified low-fat milk (FM), non-fortified low-fat milk (NFM), fortified low-fat yogurt (FY), and non-fortified low-fat yogurt (NFY). FM and FY groups were fortified with 1500 IU nano-encapsulated vitamin D3. Anthropometric parameters as well as depression, anxiety, and stress scores were measured at baseline and after a ten-week trial in Mashhad, Iran. Results: Totally, 289 participants (143 men, 146 women) with a mean age of 41.86±7.81years were enrolled in the study. There was no statistical difference between the scores of depression, anxiety, and stress in participants with and without CVD risk factors (P>0.05).  No statistical difference was found in the subgroup analysis based on milk and yogurt consumption. Conclusions: Fortified low-fat milk containing 1,500 IU of vitamin D has no impact on improving depression, anxiety, and stress during ten weeks. However, further studies with higher vitamin D doses for a longer duration are recommended.http://jnfs.ssu.ac.ir/article-1-781-en.pdfvitamin dfortificationanxietydepression
spellingShingle Payam Sharifan
Hamideh Ghazizadeh
Susan Darroudi
Alireza Ghodsi
Sara Saffar Soflaei
Davoud Tanbacoochi
Mohammad Reza Fazl Mashhadi
Mohammad Amin Mohammadi
Ali Ebrahimi dabagh
Sara Moazedi
Maryam Mohammadi Bajgiran
Gordon Ferns
Habibollah Esmaily
Majid Ghayour-Mobarhan
Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
Journal of Nutrition and Food Security
vitamin d
fortification
anxiety
depression
title Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
title_full Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
title_fullStr Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
title_full_unstemmed Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
title_short Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
title_sort effect of low fat dairy products fortified with encapsulated vitamin d3 on anxiety depression and stress in people with cardiovascular risk factors
topic vitamin d
fortification
anxiety
depression
url http://jnfs.ssu.ac.ir/article-1-781-en.pdf
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