Evaluation of selenium nanoparticles and doxorubicin effect against hepatocellular carcinoma rat model cytogenetic toxicity and DNA damage

Evaluation of selenium nanoparticles and doxorubicin effect against hepatocellular carcinoma rat model cytogenetic toxicity and DNA damage

The present study aimed to demonstrate the potent role of nanoselenium and Doxorubicin in retrogression of genotoxicity induced in hepatocellular carcinoma rat model by studying chromosomal aberration, micronuclei formation, DNA fragmentation as well as comet assay. Male rats hepatocellular carcinom...

Full description

Bibliographic Details
Main Authors:	Omaima M. Abd El-Moneim, Abeer H. Abd El-Rahim, Naglaa A. Hafiz
Format:	Article
Language:	English
Published:	Elsevier 2018-01-01
Series:	Toxicology Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750018300817

Similar Items

Galactose-modified selenium nanoparticles for targeted delivery of doxorubicin to hepatocellular carcinoma
by: Yu Xia, et al.
Published: (2019-01-01)

Functionalized Selenium Nanoparticles Enhance Anticancer Efficacy of Doxorubicin for Hepatocellular Carcinoma Therapy
by: Min Guo, et al.
Published: (2022-01-01)

The prospective protective effect of selenium nanoparticles against chromium-induced oxidative and cellular damage in rat thyroid
by: Hassanin KMA, et al.
Published: (2013-05-01)

Selenium and hepatocellular carcinoma
by: Nasar Alwahaibi,, et al.
Published: (2008)

The Roles of Doxorubicin in Hepatocellular Carcinoma
by: Kin Tam
Published: (2013-08-01)

Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats
by: Mohamed A. Dkhil, et al.
Published: (2016-11-01)

Enhancement effects of ethanolic extract of Fagonia cretica on Bisphenol A (BPA)-induced genotoxicity and biochemical changes in rats
by: Omaima Mohamed Abd-El-Moneim, et al.
Published: (2020-05-01)

The antitumour effect of galangin and luteolin with doxorubicin on chemically induced hepatocellular carcinoma in rats
by: Gamal Atwa, et al.
Published: (2021-10-01)

Selenium Nanoparticles with Prodigiosin Rescue Hippocampal Damage Associated with Epileptic Seizures Induced by Pentylenetetrazole in Rats
by: Naif E. Al Omairi, et al.
Published: (2022-02-01)

Harnessing endophytic fungi for biosynthesis of selenium nanoparticles and exploring their bioactivities
by: Heba G. Hussein, et al.
Published: (2022-06-01)

Synergistic impacts of rifampicin and doxorubicin against thioacetamide-induced hepatocellular carcinoma in rats
by: Zahraa R. Elshahawy, et al.
Published: (2023-12-01)

Chitosan/Selenium Nanoparticles Attenuate Diclofenac Sodium-Induced Testicular Toxicity in Male Rats
by: Samy M. El-Megharbel, et al.
Published: (2021-11-01)

Selenium supplementation prevents DNA damage in ram spermatozoa
by: Carla Fredrichsen Moya, et al.
Published: (2020-12-01)

Mycosynthesis of selenium nanoparticles using Penicillium tardochrysogenum as a therapeutic agent and their combination with infrared irradiation against Ehrlich carcinoma
by: Abeer I. M. EL-Sayed, et al.
Published: (2024-01-01)

Intratumoral Administration of Thermosensitive Hydrogel Co-Loaded with Norcantharidin Nanoparticles and Doxorubicin for the Treatment of Hepatocellular Carcinoma
by: Gao B, et al.
Published: (2021-06-01)

Doxorubicin-Induced Translocation of mtDNA into the Nuclear Genome of Human Lymphocytes Detected Using a Molecular-Cytogenetic Approach
by: Tigran Harutyunyan, et al.
Published: (2020-10-01)

MicroRNAs in doxorubicin-induced cardiotoxicity: The DNA damage response
by: Ippei Kawano, et al.
Published: (2022-11-01)

In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
by: Fredrik Kullenberg, et al.
Published: (2021-07-01)

Green-Synthesized Silver and Selenium Nanoparticles Using Berberine: A Comparative Assessment of In Vitro Anticancer Potential on Human Hepatocellular Carcinoma Cell Line (HepG2)
by: Azza M. Khaled, et al.
Published: (2024-02-01)

INFLUENCE OF IN-OVO INJECTION OF SELENIUM NANOPARTICLES AND SELENOMETHIONINE ON GROWTH PERFORMANCE AND PHYSIOLOGICAL PARAMETERS OF BROILER CHICKS
by: M. Abd El-Fatah, et al.
Published: (2018-10-01)

Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA-nanoparticles caused apoptosis in doxorubicin resistance breast cancer cells through induction of DNA damage
by: Sumit Siddharth, et al.
Published: (2017-05-01)

Functionalized selenium nanoparticles for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy
by: Xia Y, et al.
Published: (2018-10-01)

The role of selenium and zinc oxide nanoparticles on mitigating side effects of obesity in rats
by: A. H. Mahmoud, et al.
Published: (2022-12-01)

Albumin-Albumin/Lactosylated Core-Shell Nanoparticles: Therapy to Treat Hepatocellular Carcinoma for Controlled Delivery of Doxorubicin
by: Nayelli Guadalupe Teran-Saavedra, et al.
Published: (2020-11-01)

Effect of Zinc Oxide Nanoparticles on The Spleen of Adult Male Albino Rat and The Possible Protective Role of Selenium: Microanatomical and Biochemical Study.
by: Sara Abd El fadeel, et al.
Published: (2022-07-01)

Biogenic Selenium Nanoparticles: Anticancer, Antimicrobial, Insecticidal Properties and Their Impact on Soybean (<i>Glycine max</i> L.) Seed Germination and Seedling Growth
by: Asmaa Abdelsalam, et al.
Published: (2023-10-01)

Protective Effect of Selenium-Enriched Ricegrass Juice against Cadmium-Induced Toxicity and DNA Damage in HEK293 Kidney Cells
by: Rattanamanee Chomchan, et al.
Published: (2018-05-01)

Functionalization of selenium nanoparticles with olive polyphenols – impact on toxicity and antioxidative activity
by: Galić Emerik, et al.
Published: (2023-12-01)

Utilization of Biotechnology, Neurotransmitter and Cytogenetic Indices in Selecting Pigeon Breeds
by: MA El-Sayed, et al.
Published: (2022-12-01)

Doxorubicin-induced ovarian toxicity
by: Rizel Shulamith, et al.
Published: (2010-03-01)

Protective effects of psoralen polymer lipid nanoparticles on doxorubicin - induced myocardial toxicity
by: Fansu Meng, et al.
Published: (2022-04-01)

Hepatocellular-Targeted mRNA Delivery Using Functionalized Selenium Nanoparticles In Vitro
by: Dhireshan Singh, et al.
Published: (2021-02-01)

High Resolution and Automatable Cytogenetic Biodosimetry Using In Situ Telomere and Centromere Hybridization for the Accurate Detection of DNA Damage: An Overview
by: Radhia M’Kacher, et al.
Published: (2023-03-01)

Systemic chemotherapy with doxorubicin, cisplatin and capecitabine for metastatic hepatocellular carcinoma
by: Bang Soo-Mee, et al.
Published: (2006-01-01)

Low-density lipoprotein decorated silica nanoparticles co-delivering sorafenib and doxorubicin for effective treatment of hepatocellular carcinoma
by: Junfeng Ye, et al.
Published: (2018-01-01)

Combined treatment of sorafenib and doxorubicin-loaded microbubble-albumin nanoparticle complex for hepatocellular carcinoma: A feasibility study.
by: Seunghyun Lee, et al.
Published: (2020-01-01)

Therapeutic Impact of Costus (Saussurea lappa) Against Ehrlich Solid Tumor-Induced Cardiac Toxicity and DNA Damage in Female Mice
by: Rehab M. Elgharabawy, et al.
Published: (2021-06-01)

Testicular protective and antioxidant effects of selenium nanoparticles on Monosodium glutamate-induced testicular structure alterations in male mice
by: Reham Z. Hamza, et al.
Published: (2020-01-01)

Role of Vitamin E-Selenium in ameliorating sub chronic cadmium sulfate toxicity in rabbits
by: May J. Abd
Published: (2015-12-01)

Nephroprotective Effects of Selenium Nanoparticles Against Sodium Arsenite-Induced Damages
by: Li S, et al.
Published: (2023-06-01)