Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites
Abstract Background Recently, a simple scoring system named the Mansoura scoring system was developed to predict spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and ascites. However, the efficacy of this newly developed system has not been extensively investigated. We aimed to val...
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | BMC Gastroenterology |
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| Online Access: | https://doi.org/10.1186/s12876-023-02919-9 |
| _version_ | 1797452481714716672 |
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| author | Ngoc Cao Huynh Thong Duy Vo |
| author_facet | Ngoc Cao Huynh Thong Duy Vo |
| author_sort | Ngoc Cao Huynh |
| collection | DOAJ |
| description | Abstract Background Recently, a simple scoring system named the Mansoura scoring system was developed to predict spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and ascites. However, the efficacy of this newly developed system has not been extensively investigated. We aimed to validate a new simple scoring system for the rapid diagnosis or exclusion of SBP without paracentesis. Methods Adult patients with cirrhosis and ascites admitted to Cho Ray Hospital between November 2021 and May 2022 were included. The area under the receiver operating characteristic (AUROC) curve of the Mansoura simple scoring system for predicting SBP was calculated using the Stata software. Other independent laboratory tests for predicting SBP (C-reactive protein [CRP], neutrophil-to-lymphocyte ratio [NLR], and mean platelet volume [MPV]) were assessed and compared using the Mansoura scoring system. Results A total of 121 patients were included in this study. The Mansoura scoring system showed good performance in predicting SBP in patients with cirrhosis and ascites (AUROC:0.89). At the cut-off ≥ 4 points, the scoring system achieved a specificity of 97.7% with a positive predictive value for the diagnosis of SBP of 93.5%. Multivariate analysis was performed using our data and showed that NLR, CRP level, and MPV were independent factors related to SBP. Conclusion The Mansoura scoring system demonstrated good performance in predicting SBP in patients with cirrhosis and ascites and may help guide management decisions. |
| first_indexed | 2024-03-09T15:09:20Z |
| format | Article |
| id | doaj.art-eeeb71586cc74c0fb2638c95d92ba99e |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-03-09T15:09:20Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-eeeb71586cc74c0fb2638c95d92ba99e2023-11-26T13:30:06ZengBMCBMC Gastroenterology1471-230X2023-08-012311710.1186/s12876-023-02919-9Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascitesNgoc Cao Huynh0Thong Duy Vo1Department of Gastroenterology, Cho Ray HospitalDepartment of Gastroenterology, Cho Ray HospitalAbstract Background Recently, a simple scoring system named the Mansoura scoring system was developed to predict spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and ascites. However, the efficacy of this newly developed system has not been extensively investigated. We aimed to validate a new simple scoring system for the rapid diagnosis or exclusion of SBP without paracentesis. Methods Adult patients with cirrhosis and ascites admitted to Cho Ray Hospital between November 2021 and May 2022 were included. The area under the receiver operating characteristic (AUROC) curve of the Mansoura simple scoring system for predicting SBP was calculated using the Stata software. Other independent laboratory tests for predicting SBP (C-reactive protein [CRP], neutrophil-to-lymphocyte ratio [NLR], and mean platelet volume [MPV]) were assessed and compared using the Mansoura scoring system. Results A total of 121 patients were included in this study. The Mansoura scoring system showed good performance in predicting SBP in patients with cirrhosis and ascites (AUROC:0.89). At the cut-off ≥ 4 points, the scoring system achieved a specificity of 97.7% with a positive predictive value for the diagnosis of SBP of 93.5%. Multivariate analysis was performed using our data and showed that NLR, CRP level, and MPV were independent factors related to SBP. Conclusion The Mansoura scoring system demonstrated good performance in predicting SBP in patients with cirrhosis and ascites and may help guide management decisions.https://doi.org/10.1186/s12876-023-02919-9Spontaneous bacterial peritonitisAscitesCirrhosisPredictorsMansoura scoring system |
| spellingShingle | Ngoc Cao Huynh Thong Duy Vo Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites BMC Gastroenterology Spontaneous bacterial peritonitis Ascites Cirrhosis Predictors Mansoura scoring system |
| title | Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| title_full | Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| title_fullStr | Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| title_full_unstemmed | Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| title_short | Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| title_sort | validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites |
| topic | Spontaneous bacterial peritonitis Ascites Cirrhosis Predictors Mansoura scoring system |
| url | https://doi.org/10.1186/s12876-023-02919-9 |
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