A Species-Specific Strategy for the Identification of Hemocoagulase Agkistrodon halys pallas Based on LC-MS/MS-MRM

A Species-Specific Strategy for the Identification of Hemocoagulase Agkistrodon halys pallas Based on LC-MS/MS-MRM

Hemocoagulase Agkistrodon halys pallas is a complex mixture composed of snake venom thrombin-like enzymes (svTLEs) and small amounts of thrombokinase-like enzymes. It has been widely used as a hemostatic with rapidly growing marketing due to its advantage of localized clotting fibrinogen other than...

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Bibliographic Details
Main Authors: Ruiqing Xian, Congcong Wang, Liping Gong, Baojian Hang, Weijian Wang, Xunjie Zhang, Hongmin Du, Fengshan Wang, Feng Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
hemocoagulase
snake venom thrombin-like enzymes
marker peptide
mass spectrometry
proteomics
MRM
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.831293/full

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