FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress

FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress

Abstract Background Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), are devastating clinical disorders with high mortality, and for which more effective therapies are urgently needed. FGF1, the prototype member of the FGF family, is shown to exert protective...

Full description

Bibliographic Details
Main Authors: Qhaweni Dhlamini, Wei Wang, Guifeng Feng, Aiping Chen, Lei Chong, Xue Li, Quan Li, Jin Wu, Depu Zhou, Jie Wang, Hailin Zhang, Jin-San Zhang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Medicine
Subjects:
FGF1
Acute lung injury
Lipopolysaccharide
Inflammation
Oxidative stress
TLR4
Online Access:https://doi.org/10.1186/s10020-022-00502-8

Similar Items

Similar Items