AhR, PXR and CAR: From Xenobiotic Receptors to Metabolic Sensors
Traditionally, xenobiotic receptors are known for their role in chemical sensing and detoxification, as receptor activation regulates the expression of various key enzymes and receptors. However, recent studies have highlighted that xenobiotic receptors also play a key role in the regulation of lipi...
Main Authors: | Leonida Rakateli, Rosanna Huchzermeier, Emiel P. C. van der Vorst |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/12/23/2752 |
Similar Items
-
Atypical functions of xenobiotic receptors in lipid and glucose metabolism
by: Wang Jingyuan, et al.
Published: (2022-11-01) -
A brief history of the discovery of PXR and CAR as xenobiotic receptors
by: Jiong Yan, et al.
Published: (2016-09-01) -
Modulation of Xenobiotic Receptors by Steroids
by: Delira Robbins, et al.
Published: (2013-06-01) -
Transporter Gene Regulation in Sandwich Cultured Human Hepatocytes Through the Activation of Constitutive Androstane Receptor (CAR) or Aryl Hydrocarbon Receptor (AhR)
by: Congrong Niu, et al.
Published: (2021-01-01) -
Regulation of High-Altitude Hypoxia on the Transcription of CYP450 and UGT1A1 Mediated by PXR and CAR
by: Ya-bin Duan, et al.
Published: (2020-09-01)