Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism
Drug addiction is one of the major worldwide health problems, which will have serious adverse consequences on human health and significantly burden the social economy and public health. Drug abuse is more common in anesthesiologists than in the general population because of their easier access to co...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/9/1259 |
| _version_ | 1827726970551533568 |
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| author | Liyun Deng Lining Wu Rui Gao Xiaolin Xu Chan Chen Jin Liu |
| author_facet | Liyun Deng Lining Wu Rui Gao Xiaolin Xu Chan Chen Jin Liu |
| author_sort | Liyun Deng |
| collection | DOAJ |
| description | Drug addiction is one of the major worldwide health problems, which will have serious adverse consequences on human health and significantly burden the social economy and public health. Drug abuse is more common in anesthesiologists than in the general population because of their easier access to controlled substances. Although opioids have been generally considered the most commonly abused drugs among anesthesiologists and nurse anesthetists, the abuse of non-opioid anesthetics has been increasingly severe in recent years. The purpose of this review is to provide an overview of the clinical situation and potential molecular mechanisms of non-opioid anesthetics addiction. This review incorporates the clinical and biomolecular evidence supporting the abuse potential of non-opioid anesthetics and the foreseeable mechanism causing the non-opioid anesthetics addiction phenotypes, promoting a better understanding of its pathogenesis and helping to find effective preventive and curative strategies. |
| first_indexed | 2024-03-10T22:59:52Z |
| format | Article |
| id | doaj.art-eef77211c6f9428a8737c114b9d9720e |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T22:59:52Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-eef77211c6f9428a8737c114b9d9720e2023-11-19T09:48:28ZengMDPI AGBrain Sciences2076-34252023-08-01139125910.3390/brainsci13091259Non-Opioid Anesthetics Addiction: A Review of Current Situation and MechanismLiyun Deng0Lining Wu1Rui Gao2Xiaolin Xu3Chan Chen4Jin Liu5Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDrug addiction is one of the major worldwide health problems, which will have serious adverse consequences on human health and significantly burden the social economy and public health. Drug abuse is more common in anesthesiologists than in the general population because of their easier access to controlled substances. Although opioids have been generally considered the most commonly abused drugs among anesthesiologists and nurse anesthetists, the abuse of non-opioid anesthetics has been increasingly severe in recent years. The purpose of this review is to provide an overview of the clinical situation and potential molecular mechanisms of non-opioid anesthetics addiction. This review incorporates the clinical and biomolecular evidence supporting the abuse potential of non-opioid anesthetics and the foreseeable mechanism causing the non-opioid anesthetics addiction phenotypes, promoting a better understanding of its pathogenesis and helping to find effective preventive and curative strategies.https://www.mdpi.com/2076-3425/13/9/1259drug addictionsubstance use disordersnon-opioid anesthetics |
| spellingShingle | Liyun Deng Lining Wu Rui Gao Xiaolin Xu Chan Chen Jin Liu Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism Brain Sciences drug addiction substance use disorders non-opioid anesthetics |
| title | Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism |
| title_full | Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism |
| title_fullStr | Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism |
| title_full_unstemmed | Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism |
| title_short | Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism |
| title_sort | non opioid anesthetics addiction a review of current situation and mechanism |
| topic | drug addiction substance use disorders non-opioid anesthetics |
| url | https://www.mdpi.com/2076-3425/13/9/1259 |
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