Metabolic Effects of Selective Deletion of Group VIA Phospholipase A<sub>2</sub> from Macrophages or Pancreatic Islet Beta-Cells

Metabolic Effects of Selective Deletion of Group VIA Phospholipase A<sub>2</sub> from Macrophages or Pancreatic Islet Beta-Cells

To examine the role of group VIA phospholipase A<sub>2</sub> (iPLA<sub>2</sub>β) in specific cell lineages in insulin secretion and insulin action, we prepared mice with a selective iPLA<sub>2</sub>β deficiency in cells of myelomonocytic lineage, including macroph...

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Bibliographic Details
Main Authors: John Turk, Haowei Song, Mary Wohltmann, Cheryl Frankfater, Xiaoyong Lei, Sasanka Ramanadham
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
pancreatic islets
β-cells
insulin secretion
glucose tolerance
insulin resistance
group VIA phospholipase A<sub>2</sub>
Online Access:https://www.mdpi.com/2218-273X/10/10/1455

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