Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
Ascomylactam C (AsC) is a new 13-membered-ring macrocyclic alkaloid, which was first isolated and identified in 2019 from the secondary metabolites of the mangrove endophytic fungus <i>Didymella</i> sp. CYSK-4 in the South China Sea. AsC has been found to have a broad-spectrum cytotoxic...
Main Authors: | Yun Huang, Hongmei Yan, Bingzhi Zhang, Ge Zhu, Jianchen Yu, Xuhan Xiao, Wenxuan He, Yan Chen, Xiaoxia Gao, Zhigang She, Mengfeng Li, Jie Yuan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/21/12/600 |
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