Peripheral chemoreflex modulation of renal hemodynamics and renal tissue PO2 in chronic heart failure with reduced ejection fraction

Peripheral chemoreflex modulation of renal hemodynamics and renal tissue PO2 in chronic heart failure with reduced ejection fraction

Aberrant carotid body chemoreceptor (CBC) function contributes to increased sympathetic nerve activity (SNA) and reduced renal blood flow (RBF) in chronic heart failure (CHF). Intermittent asphyxia (IA) mimicking sleep apnea is associated with additional increases in SNA and may worsen reductions in...

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Bibliographic Details
Main Authors: Kiefer W. Kious, Andrew Philipose, Luke J. Smith, Jayson P. Kemble, Stephanie C. E. Twohey, Kalie Savage, Hugo S. Díaz, Rodrigo Del Rio, Noah J. Marcus
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
Subjects:
heart failure
cardio renal syndrome (CRS)
carotid body chemoreflex
carotid body denervation (CBD)
renal blood flow (RBF)
renal oxygenation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.955538/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.955538/full

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