Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study
Introduction: Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) causing Coronavirus Disease (COVID-19) has challenged the world. A complete blood workup as well as continuous tracking of haematological parameters play a vital role in revealing the risks of disease progression and eve...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2022-01-01
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| Series: | National Journal of Laboratory Medicine |
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| Online Access: | https://www.njlm.net/articles/PDF/2568/50591_CE[Ra1]_F[SH]_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
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| author | Shashi Upreti Snigdha Petwal Anupama Arya Aditi Upreti Narayan Mihir Sana Umar |
| author_facet | Shashi Upreti Snigdha Petwal Anupama Arya Aditi Upreti Narayan Mihir Sana Umar |
| author_sort | Shashi Upreti |
| collection | DOAJ |
| description | Introduction: Severe Acute Respiratory Syndrome Corona
Virus-2 (SARS-CoV-2) causing Coronavirus Disease (COVID-19)
has challenged the world. A complete blood workup as well as
continuous tracking of haematological parameters play a vital
role in revealing the risks of disease progression and eventually
help in better treatment and outcome.
Aim: To access the haematological parameters {Complete Blood
Count (CBC), Neutrophil Lymphocyte Ratio (NLR) and Serum
Ferritin (S. ferritin) levels} in COVID-19 patients to correlate its
association with the severity of the disease.
Materials and Methods: The present study was a cross-sectional
study in which 200 patients who were confirmed as COVID-19
positive by real time Reverse Transcriptase-Polymerase Chain
Reaction (RT-PCR) in the month of July-August 2020 were
included. Blood was collected from patients of COVID-19 using
the routine methods and was evaluated for CBC and S. ferritin
levels. Neutrophil Lymphocyte Ratio (NLR) was also calculated.
Results: The NLR was positively correlated with severity of
COVID-19. Patients with higher NLR levels were admitted to
Intensive Care Unit (ICU) because of severity in their condition.
In the present study, 42 of 47 (89.4%) ICU patients had S. ferritin
levels >1000 ng/mL whereas only 8 (5.2%) of non ICU patients
had S. ferritin levels >1000 ng/mL.
Conclusion: The NLR and S. ferritin positively correlated with
the severity of COVID-19 disease.
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| first_indexed | 2024-12-18T06:38:13Z |
| format | Article |
| id | doaj.art-ef08e67f1ed3473fac341d82a70d8a4b |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-12-18T06:38:13Z |
| publishDate | 2022-01-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-ef08e67f1ed3473fac341d82a70d8a4b2022-12-21T21:17:43ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822022-01-011101121410.7860/NJLM/2022/50591.2568Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional StudyShashi UpretiSnigdha PetwalAnupama AryaAditi UpretiNarayan MihirSana UmarIntroduction: Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) causing Coronavirus Disease (COVID-19) has challenged the world. A complete blood workup as well as continuous tracking of haematological parameters play a vital role in revealing the risks of disease progression and eventually help in better treatment and outcome. Aim: To access the haematological parameters {Complete Blood Count (CBC), Neutrophil Lymphocyte Ratio (NLR) and Serum Ferritin (S. ferritin) levels} in COVID-19 patients to correlate its association with the severity of the disease. Materials and Methods: The present study was a cross-sectional study in which 200 patients who were confirmed as COVID-19 positive by real time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) in the month of July-August 2020 were included. Blood was collected from patients of COVID-19 using the routine methods and was evaluated for CBC and S. ferritin levels. Neutrophil Lymphocyte Ratio (NLR) was also calculated. Results: The NLR was positively correlated with severity of COVID-19. Patients with higher NLR levels were admitted to Intensive Care Unit (ICU) because of severity in their condition. In the present study, 42 of 47 (89.4%) ICU patients had S. ferritin levels >1000 ng/mL whereas only 8 (5.2%) of non ICU patients had S. ferritin levels >1000 ng/mL. Conclusion: The NLR and S. ferritin positively correlated with the severity of COVID-19 disease. https://www.njlm.net/articles/PDF/2568/50591_CE[Ra1]_F[SH]_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdfcomplete blood countcoronavirus disease-2019serum inflammatory markerssevere acute respiratory syndrome 2 |
| spellingShingle | Shashi Upreti Snigdha Petwal Anupama Arya Aditi Upreti Narayan Mihir Sana Umar Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study National Journal of Laboratory Medicine complete blood count coronavirus disease-2019 serum inflammatory markers severe acute respiratory syndrome 2 |
| title | Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study |
| title_full | Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study |
| title_fullStr | Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study |
| title_full_unstemmed | Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study |
| title_short | Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study |
| title_sort | neutrophil lymphocyte ratio and serum ferritin levels in covid 19 a cross sectional study |
| topic | complete blood count coronavirus disease-2019 serum inflammatory markers severe acute respiratory syndrome 2 |
| url | https://www.njlm.net/articles/PDF/2568/50591_CE[Ra1]_F[SH]_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
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