The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks

The eukaryotic nucleus is continuously being exposed to endogenous and exogenous sources that cause DNA breaks, whose faithful repair requires the activity of dedicated nuclear machineries. DNA is packaged into a variety of chromatin domains, each characterized by specific molecular properties that...

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Bibliographic Details
Main Authors: Apfrida Kendek, Marieke R. Wensveen, Aniek Janssen
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/9/1415