Structural heterogeneity assessment among the isoforms of fungal 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase: a comparative in silico perspective

Highlights • First comprehensive in silico annotation of fungal ACC deaminases (fACCD). • Colletotrichum, Fusarium, and Trichoderma are predominant to possess fACCD. • fACCD are 16.18–82.47 kDa proteins with optimal pH between 4.76 and 10.06. • Majority are thermostable with higher aliphatic indices...

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Bibliographic Details
Main Authors: Krishnendu Pramanik, Narayan Chandra Mandal
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s43141-021-00294-0
Description
Summary:Highlights • First comprehensive in silico annotation of fungal ACC deaminases (fACCD). • Colletotrichum, Fusarium, and Trichoderma are predominant to possess fACCD. • fACCD are 16.18–82.47 kDa proteins with optimal pH between 4.76 and 10.06. • Majority are thermostable with higher aliphatic indices and instability indices < 40. • fACCD are found as homo-dimer except ACCNK13, a homo-tetramer. Graphical Abstract
ISSN:2090-5920