Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats

Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats

Previous experiments in animals and humans show that shifts in microbiota and its metabolites are linked to hypertension. The present study investigates whether doxycycline (DOX, a broad-spectrum tetracycline antibiotic) improves dysbiosis, prevent cardiovascular pathology and attenuate hypertension...

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Bibliographic Details
Main Authors: Iñaki Robles-Vera, Néstor de la Visitación, Marta Toral, Manuel Sánchez, Miguel Romero, Manuel Gómez-Guzmán, Félix Vargas, Juan Duarte, Rosario Jiménez
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Nutrients
Subjects:
doxycycline
gut dysbiosis
hypertension
oxidative stress
inflammation
DOCA-salt model
Online Access:https://www.mdpi.com/2072-6643/13/9/2971

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