Colloidal Self-Assembled Patterns Maintain the Pluripotency and Promote the Hemopoietic Potential of Human Embryonic Stem Cells

Colloidal Self-Assembled Patterns Maintain the Pluripotency and Promote the Hemopoietic Potential of Human Embryonic Stem Cells

The generation of blood cells in a significant amount for clinical uses is still challenging. Human pluripotent stem cells-derived hemopoietic cells (hPSC-HCs) are a promising cell source to generate blood cells. Previously, it has been shown that the attached substrates are crucial in the maintenan...

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Bibliographic Details
Main Authors: Jiao Lin, Jiahui Zeng, Wencui Sun, Kun Liu, Myagmartsend Enkhbat, Danying Yi, Javad Harati, Jiaxin Liu, Peter Kingshott, Bo Chen, Feng Ma, Peng-Yuan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
colloidal self-assembly
artificial ECM
pluripotent stem cells
hematopoiesis
blood cells
focal adhesion
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.771773/full

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