Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R

Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R

IntroductionDengue is an arthropod-born disease caused by dengue virus (DENV), that may manifest as a mild illness or severe form, characterized by hemorrhagic fever and shock. Nitric oxide (NO) is a vasodilator signaling molecule and an inhibitor of platelet aggregation known to be increased in pla...

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Main Authors: Mariana Brandi Mendonça Pinheiro, Stephane Vicente Rozini, Anna Cecíllia Quirino-Teixeira, Giselle Barbosa-Lima, Juliana F. Lopes, Carolina Q. Sacramento, Fernando A. Bozza, Patrícia T. Bozza, Eugenio D. Hottz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
platelets
nitric oxide
iNOS
IL-1R
dengue
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1029213/full

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