An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature
Ecchordosis physaliphora (EP) is a benign notochordal remnant, which is often an incidental finding; however, it can rarely present with neurological symptoms. We performed a systematic review of the literature for cases of symptomatic EP published in PubMed, Web of Science and Embase from January 1...
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| Format: | Article |
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MDPI AG
2023-09-01
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| Series: | Neurology International |
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| Online Access: | https://www.mdpi.com/2035-8377/15/4/75 |
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| author | Rajesh K. Gupta Thejasvi A. Reddy Ashutosh Gupta Rohan Samant Carlos A. Perez Anam Haque |
| author_facet | Rajesh K. Gupta Thejasvi A. Reddy Ashutosh Gupta Rohan Samant Carlos A. Perez Anam Haque |
| author_sort | Rajesh K. Gupta |
| collection | DOAJ |
| description | Ecchordosis physaliphora (EP) is a benign notochordal remnant, which is often an incidental finding; however, it can rarely present with neurological symptoms. We performed a systematic review of the literature for cases of symptomatic EP published in PubMed, Web of Science and Embase from January 1982 to May 2023. This is the largest review to date and revealed 60 cases including ours. Headache (55%) and CSF rhinorrhea (32%) were the most frequent clinical manifestations. The majority of symptomatic EP lesions were located in the prepontine region (77%) and required surgical resection (75%). EP should be considered in patients with neurologic symptoms in the setting of prepontine or posterior sphenoid sinus lesions. While symptomatic patients often require surgical intervention, rare cases may respond to oral corticosteroids. |
| first_indexed | 2024-03-08T20:29:30Z |
| format | Article |
| id | doaj.art-ef1f9cdcbe934487beea395755758f87 |
| institution | Directory Open Access Journal |
| issn | 2035-8377 |
| language | English |
| last_indexed | 2024-03-08T20:29:30Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Neurology International |
| spelling | doaj.art-ef1f9cdcbe934487beea395755758f872023-12-22T14:29:30ZengMDPI AGNeurology International2035-83772023-09-011541200121110.3390/neurolint15040075An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the LiteratureRajesh K. Gupta0Thejasvi A. Reddy1Ashutosh Gupta2Rohan Samant3Carlos A. Perez4Anam Haque5Division of Multiple Sclerosis and Neuroimmunology, Department of Neurology, University of Texas Health Science Center, Houston, TX 77030, USAMcGovern Medical School, UT Health Science Center, Houston, TX 77030, USAMcGovern Medical School, UT Health Science Center, Houston, TX 77030, USADepartment of Radiology, UT Health Science Center, Houston, TX 77030, USADepartment of Neurology, Baylor College of Medicine, Houston, TX 77030, USAMcGovern Medical School, UT Health Science Center, Houston, TX 77030, USAEcchordosis physaliphora (EP) is a benign notochordal remnant, which is often an incidental finding; however, it can rarely present with neurological symptoms. We performed a systematic review of the literature for cases of symptomatic EP published in PubMed, Web of Science and Embase from January 1982 to May 2023. This is the largest review to date and revealed 60 cases including ours. Headache (55%) and CSF rhinorrhea (32%) were the most frequent clinical manifestations. The majority of symptomatic EP lesions were located in the prepontine region (77%) and required surgical resection (75%). EP should be considered in patients with neurologic symptoms in the setting of prepontine or posterior sphenoid sinus lesions. While symptomatic patients often require surgical intervention, rare cases may respond to oral corticosteroids.https://www.mdpi.com/2035-8377/15/4/75ecchordosis physaliphoranotochordchordomaCNS |
| spellingShingle | Rajesh K. Gupta Thejasvi A. Reddy Ashutosh Gupta Rohan Samant Carlos A. Perez Anam Haque An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature Neurology International ecchordosis physaliphora notochord chordoma CNS |
| title | An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature |
| title_full | An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature |
| title_fullStr | An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature |
| title_full_unstemmed | An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature |
| title_short | An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature |
| title_sort | ecchordosis physaliphora a rare entity involving the central nervous system a systematic review of the literature |
| topic | ecchordosis physaliphora notochord chordoma CNS |
| url | https://www.mdpi.com/2035-8377/15/4/75 |
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