Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection
Abstract Objectives Nontypeable Haemophilus influenzae (NTHi) is an important human respiratory bacterium that can cause a range of diseases including sinusitis, otitis media, conjunctivitis, pneumonia as well as acute exacerbations of chronic obstructive pulmonary disease (COPD). A number of studie...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-04-01
|
| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13104-021-05528-5 |
| _version_ | 1818948981732933632 |
|---|---|
| author | Rajendra KC Ronan F. O’Toole |
| author_facet | Rajendra KC Ronan F. O’Toole |
| author_sort | Rajendra KC |
| collection | DOAJ |
| description | Abstract Objectives Nontypeable Haemophilus influenzae (NTHi) is an important human respiratory bacterium that can cause a range of diseases including sinusitis, otitis media, conjunctivitis, pneumonia as well as acute exacerbations of chronic obstructive pulmonary disease (COPD). A number of studies have used NTHi clinical isolate RHH-3 as a laboratory strain for experimentation examining the effect of cigarette smoke and more recently, biomass smoke, on the susceptibility and response of cells lining the respiratory tract to infection. Therefore, definition of the genome content of RHH-3 is required to fully elucidate human-NTHi interactions associated with initial infection and subsequent development of respiratory disease. Data description Here, we present the draft genome sequence of NTHi RHH-3 collected from the sputum of a patient at the Royal Hobart Hospital, Tasmania, Australia. The assembled genome size was 1,839,376 bp consisting of 61 contigs (> 500 bp), with a G+C content of 38.1%. This draft genome data can be accessed at DDBJ/ENA/GenBank under the accession number JADPRR000000000. |
| first_indexed | 2024-12-20T08:55:26Z |
| format | Article |
| id | doaj.art-ef20ff0b5731472a9c4ccf0a3e08e779 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-20T08:55:26Z |
| publishDate | 2021-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-ef20ff0b5731472a9c4ccf0a3e08e7792022-12-21T19:46:01ZengBMCBMC Research Notes1756-05002021-04-011411410.1186/s13104-021-05528-5Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infectionRajendra KC0Ronan F. O’Toole1Menzies Institute for Medical Research, University of TasmaniaDepartment of Pharmacy and Biomedical Sciences, School of Molecular Sciences, College of Science, Health and Engineering, La Trobe UniversityAbstract Objectives Nontypeable Haemophilus influenzae (NTHi) is an important human respiratory bacterium that can cause a range of diseases including sinusitis, otitis media, conjunctivitis, pneumonia as well as acute exacerbations of chronic obstructive pulmonary disease (COPD). A number of studies have used NTHi clinical isolate RHH-3 as a laboratory strain for experimentation examining the effect of cigarette smoke and more recently, biomass smoke, on the susceptibility and response of cells lining the respiratory tract to infection. Therefore, definition of the genome content of RHH-3 is required to fully elucidate human-NTHi interactions associated with initial infection and subsequent development of respiratory disease. Data description Here, we present the draft genome sequence of NTHi RHH-3 collected from the sputum of a patient at the Royal Hobart Hospital, Tasmania, Australia. The assembled genome size was 1,839,376 bp consisting of 61 contigs (> 500 bp), with a G+C content of 38.1%. This draft genome data can be accessed at DDBJ/ENA/GenBank under the accession number JADPRR000000000.https://doi.org/10.1186/s13104-021-05528-5Whole genome sequenceNontypeable Haemophilus influenzaeChronic obstructive pulmonary disease |
| spellingShingle | Rajendra KC Ronan F. O’Toole Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection BMC Research Notes Whole genome sequence Nontypeable Haemophilus influenzae Chronic obstructive pulmonary disease |
| title | Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection |
| title_full | Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection |
| title_fullStr | Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection |
| title_full_unstemmed | Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection |
| title_short | Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection |
| title_sort | draft genome sequence of a nontypeable haemophilus influenzae strain used in the study of human respiratory infection |
| topic | Whole genome sequence Nontypeable Haemophilus influenzae Chronic obstructive pulmonary disease |
| url | https://doi.org/10.1186/s13104-021-05528-5 |
| work_keys_str_mv | AT rajendrakc draftgenomesequenceofanontypeablehaemophilusinfluenzaestrainusedinthestudyofhumanrespiratoryinfection AT ronanfotoole draftgenomesequenceofanontypeablehaemophilusinfluenzaestrainusedinthestudyofhumanrespiratoryinfection |