Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa
Spilanthes mauritiana belonging to the family Asteraceae, was screened for biological activity against bacterial pathogen. Antibacterial activity of the plant was investigated using microbroth dilution assay and bioautography. Total phenols and tannins of the extract were 52.47 ± 2.29 and 23.9 ± 1.1...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-10-01
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| Series: | Journal of Evidence-Based Complementary & Alternative Medicine |
| Online Access: | https://doi.org/10.1177/2515690X17746774 |
| _version_ | 1818294789500567552 |
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| author | Peter Masoko PhD |
| author_facet | Peter Masoko PhD |
| author_sort | Peter Masoko PhD |
| collection | DOAJ |
| description | Spilanthes mauritiana belonging to the family Asteraceae, was screened for biological activity against bacterial pathogen. Antibacterial activity of the plant was investigated using microbroth dilution assay and bioautography. Total phenols and tannins of the extract were 52.47 ± 2.29 and 23.9 ± 1.18 as mg of gallic acid equivalents, respectively. Total flavonoid content was 25.1 ± 0.79 as mg of quercetin equivalents. Free radical scavenging activity of constituents in all the extract, against 2,2-diphenyl-1-picrylhydrazyl showed minimal activity. All extracts contained compounds with antibacterial activity against tested pathogens. Hexane extract had an average minimum inhibitory concentration value of 2.50 mg/mL, followed by methanol extract (1.72 mg/mL), acetone and dichloromethane extracts (1.96 mg/mL). The present study revealed the presence of compounds in S mauritiana with potent antibacterial activity against tested pathogens that are exhibiting the observed activity independent of other constituents contained in the extracts. |
| first_indexed | 2024-12-13T03:37:20Z |
| format | Article |
| id | doaj.art-ef218d8baf254271b49089467f45f610 |
| institution | Directory Open Access Journal |
| issn | 2156-5872 2156-5899 |
| language | English |
| last_indexed | 2024-12-13T03:37:20Z |
| publishDate | 2017-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Evidence-Based Complementary & Alternative Medicine |
| spelling | doaj.art-ef218d8baf254271b49089467f45f6102022-12-22T00:01:01ZengSAGE PublishingJournal of Evidence-Based Complementary & Alternative Medicine2156-58722156-58992017-10-012210.1177/2515690X17746774Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South AfricaPeter Masoko PhD0 University of Limpopo, Sovenga, South AfricaSpilanthes mauritiana belonging to the family Asteraceae, was screened for biological activity against bacterial pathogen. Antibacterial activity of the plant was investigated using microbroth dilution assay and bioautography. Total phenols and tannins of the extract were 52.47 ± 2.29 and 23.9 ± 1.18 as mg of gallic acid equivalents, respectively. Total flavonoid content was 25.1 ± 0.79 as mg of quercetin equivalents. Free radical scavenging activity of constituents in all the extract, against 2,2-diphenyl-1-picrylhydrazyl showed minimal activity. All extracts contained compounds with antibacterial activity against tested pathogens. Hexane extract had an average minimum inhibitory concentration value of 2.50 mg/mL, followed by methanol extract (1.72 mg/mL), acetone and dichloromethane extracts (1.96 mg/mL). The present study revealed the presence of compounds in S mauritiana with potent antibacterial activity against tested pathogens that are exhibiting the observed activity independent of other constituents contained in the extracts.https://doi.org/10.1177/2515690X17746774 |
| spellingShingle | Peter Masoko PhD Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa Journal of Evidence-Based Complementary & Alternative Medicine |
| title | Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa |
| title_full | Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa |
| title_fullStr | Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa |
| title_full_unstemmed | Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa |
| title_short | Phytochemical Analysis, Antioxidant and Antibacterial Properties of Used Traditionally in Limpopo Province, South Africa |
| title_sort | phytochemical analysis antioxidant and antibacterial properties of used traditionally in limpopo province south africa |
| url | https://doi.org/10.1177/2515690X17746774 |
| work_keys_str_mv | AT petermasokophd phytochemicalanalysisantioxidantandantibacterialpropertiesofusedtraditionallyinlimpopoprovincesouthafrica |