Long-read sequencing identifies novel structural variations in colorectal cancer.

Long-read sequencing identifies novel structural variations in colorectal cancer.

Structural variations (SVs) are a key type of cancer genomic alterations, contributing to oncogenesis and progression of many cancers, including colorectal cancer (CRC). However, SVs in CRC remain difficult to be reliably detected due to limited SV-detection capacity of the commonly used short-read...

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Bibliographic Details
Main Authors:	Luming Xu, Xingyue Wang, Xiaohuan Lu, Fan Liang, Zhibo Liu, Hongyan Zhang, Xiaoqiong Li, ShaoBo Tian, Lin Wang, Zheng Wang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-02-01
Series:	PLoS Genetics
Online Access:	https://doi.org/10.1371/journal.pgen.1010514

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