Long-read sequencing identifies novel structural variations in colorectal cancer.
Structural variations (SVs) are a key type of cancer genomic alterations, contributing to oncogenesis and progression of many cancers, including colorectal cancer (CRC). However, SVs in CRC remain difficult to be reliably detected due to limited SV-detection capacity of the commonly used short-read...
Main Authors: | Luming Xu, Xingyue Wang, Xiaohuan Lu, Fan Liang, Zhibo Liu, Hongyan Zhang, Xiaoqiong Li, ShaoBo Tian, Lin Wang, Zheng Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-02-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1010514 |
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