Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability

Decision-making at the border of viability remains challenging for the expectant parents and the medical team. The preterm infant is dependent on others making the decision that will impact them for a lifetime in hopefully their best interest. Besides survival and survival without neurodevelopmental...

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Main Authors: Rahel Schuler, Ivonne Bedei, Frank Oehmke, Klaus-Peter Zimmer, Harald Ehrhardt
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/9/3/313
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author Rahel Schuler
Ivonne Bedei
Frank Oehmke
Klaus-Peter Zimmer
Harald Ehrhardt
author_facet Rahel Schuler
Ivonne Bedei
Frank Oehmke
Klaus-Peter Zimmer
Harald Ehrhardt
author_sort Rahel Schuler
collection DOAJ
description Decision-making at the border of viability remains challenging for the expectant parents and the medical team. The preterm infant is dependent on others making the decision that will impact them for a lifetime in hopefully their best interest. Besides survival and survival without neurodevelopmental impairment, other relevant outcome measures, such as the quality of life of former preterm infants and the impact on family life, need to be integrated into prenatal counselling. Recommendations and national guidelines continue to rely on arbitrarily set gestational age limits at which treatment is not recommended, can be considered and it is recommended. These guidelines neglect other individual prognostic outcome factors like antenatal steroids, birth weight and gender. Besides individual factors, centre-specific factors like perinatal treatment intensity and the attitude of healthcare professionals significantly determine the futures of these infants at the border of viability. A more comprehensive approach regarding treatment recommendations and relevant outcome measures is necessary.
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spelling doaj.art-ef27a71912264cac8ec978631f110d622023-11-24T00:46:21ZengMDPI AGChildren2227-90672022-02-019331310.3390/children9030313Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of ViabilityRahel Schuler0Ivonne Bedei1Frank Oehmke2Klaus-Peter Zimmer3Harald Ehrhardt4Department of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, GermanyDepartment of Obstetrics and Gynecology, Justus-Liebig-University, Klinikstrasse 33, 35392 Giessen, GermanyDepartment of Obstetrics and Gynecology, Justus-Liebig-University, Klinikstrasse 33, 35392 Giessen, GermanyDepartment of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, GermanyDepartment of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, GermanyDecision-making at the border of viability remains challenging for the expectant parents and the medical team. The preterm infant is dependent on others making the decision that will impact them for a lifetime in hopefully their best interest. Besides survival and survival without neurodevelopmental impairment, other relevant outcome measures, such as the quality of life of former preterm infants and the impact on family life, need to be integrated into prenatal counselling. Recommendations and national guidelines continue to rely on arbitrarily set gestational age limits at which treatment is not recommended, can be considered and it is recommended. These guidelines neglect other individual prognostic outcome factors like antenatal steroids, birth weight and gender. Besides individual factors, centre-specific factors like perinatal treatment intensity and the attitude of healthcare professionals significantly determine the futures of these infants at the border of viability. A more comprehensive approach regarding treatment recommendations and relevant outcome measures is necessary.https://www.mdpi.com/2227-9067/9/3/313extremely preterm infantborder of viabilitydecision-makingoutcome measuressurvivalsurvival without disability
spellingShingle Rahel Schuler
Ivonne Bedei
Frank Oehmke
Klaus-Peter Zimmer
Harald Ehrhardt
Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
Children
extremely preterm infant
border of viability
decision-making
outcome measures
survival
survival without disability
title Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
title_full Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
title_fullStr Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
title_full_unstemmed Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
title_short Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability
title_sort neonatal outcome and treatment perspectives of preterm infants at the border of viability
topic extremely preterm infant
border of viability
decision-making
outcome measures
survival
survival without disability
url https://www.mdpi.com/2227-9067/9/3/313
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