BONEFILL ® block as alternative for bone substitute: a toxicological evaluation

ABSTRACT Bone substitutes based on hydroxyapatite (HA) and Bonefill® (BO - inorganic bovine bone) associated with poly(lactic-co-glycolic acid) (PLGA) (HA/PLGA and BO/PLGA) were evaluated concerning cytotoxicity, genotoxicity and mutagenicity as potential candidates for bone repair. The materials we...

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Bibliographic Details
Main Authors: Karine Melchior, Sybele Saska, Fernanda Coelho, Raquel Mantuaneli Scarel-Caminaga, Ticiana Sidorenko de Oliveira Capote
Format: Article
Language:English
Published: Universidade de São Paulo 2018-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200611&lng=en&tlng=en