Decoding lymphomyeloid divergence and immune hyporesponsiveness in G-CSF-primed human bone marrow by single-cell RNA-seq

Decoding lymphomyeloid divergence and immune hyporesponsiveness in G-CSF-primed human bone marrow by single-cell RNA-seq

Abstract Granulocyte colony-stimulating factor (G-CSF) has been widely used to mobilize bone marrow hematopoietic stem/progenitor cells for transplantation in the treatment of hematological malignancies for decades. Additionally, G-CSF is also accepted as an essential mediator in immune regulation,...

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Bibliographic Details
Main Authors: Guoju You, Man Zhang, Zhilei Bian, Huidong Guo, Zhengyang Xu, Yanli Ni, Yu Lan, Wen Yue, Yandong Gong, Yingjun Chang, Xiaojun Huang, Bing Liu
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00417-y

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