Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides
Over the years, extensive use of commercially available synthetic pesticides against phytophagous insects has led to their bioaccumulation in the environment causing increased resistance and reduction in soil biodiversity. Further, 90% of the applied pesticides enter the various environmental resour...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-05-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fpls.2017.00610/full |
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| author | Suman Chaudhary Rupinder K. Kanwar Alka Sehgal David M. Cahill Colin J. Barrow Rakesh Sehgal Jagat R. Kanwar |
| author_facet | Suman Chaudhary Rupinder K. Kanwar Alka Sehgal David M. Cahill Colin J. Barrow Rakesh Sehgal Jagat R. Kanwar |
| author_sort | Suman Chaudhary |
| collection | DOAJ |
| description | Over the years, extensive use of commercially available synthetic pesticides against phytophagous insects has led to their bioaccumulation in the environment causing increased resistance and reduction in soil biodiversity. Further, 90% of the applied pesticides enter the various environmental resources as a result of run-off, exposing the farmers as well as consumers of the agricultural produce to severe health issues. Therefore, growing attention has been given toward the development of alternate environmentally friendly pesticides/insecticides that would aid an efficient pest management system and also prevent chronic exposures leading to diseases. One such strategy is, the use of neem plant's (Binomial name: Azadirachta indica) active ingredients which exhibit agro-medicinal properties conferring insecticidal as well as immunomodulatory and anti-cancer properties. The most prominent constituent of neem is azadirachtin, which has been established as a pivotal insecticidal ingredient. It acts as an antifeedant, repellent, and repugnant agent and induces sterility in insects by preventing oviposition and interrupting sperm production in males. This review discusses, key neem pesticidal components, their active functional ingredients along with recent strategies on employing nanocarriers, to provide controlled release of the active ingredients and to improve their stability and sustainability. |
| first_indexed | 2024-12-20T07:36:36Z |
| format | Article |
| id | doaj.art-ef31b4c6e7d445af9fa4e45309528df1 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-20T07:36:36Z |
| publishDate | 2017-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-ef31b4c6e7d445af9fa4e45309528df12022-12-21T19:48:16ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2017-05-01810.3389/fpls.2017.00610226969Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic PesticidesSuman Chaudhary0Rupinder K. Kanwar1Alka Sehgal2David M. Cahill3Colin J. Barrow4Rakesh Sehgal5Jagat R. Kanwar6Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research, Faculty of Health, Centre for Molecular and Medical Research, Strategic Research Centre, School of Medicine, Deakin UniversityGeelong, VIC, AustraliaNanomedicine-Laboratory of Immunology and Molecular Biomedical Research, Faculty of Health, Centre for Molecular and Medical Research, Strategic Research Centre, School of Medicine, Deakin UniversityGeelong, VIC, AustraliaDepartment of Gynecology, Government Medical College and HospitalChandigarh, IndiaCentre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin UniversityGeelong, VIC, AustraliaCentre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin UniversityGeelong, VIC, AustraliaDepartment of Medical Parasitology, Jawaharlal Institute of Postgraduate Medical Education and ResearchChandigarh, IndiaNanomedicine-Laboratory of Immunology and Molecular Biomedical Research, Faculty of Health, Centre for Molecular and Medical Research, Strategic Research Centre, School of Medicine, Deakin UniversityGeelong, VIC, AustraliaOver the years, extensive use of commercially available synthetic pesticides against phytophagous insects has led to their bioaccumulation in the environment causing increased resistance and reduction in soil biodiversity. Further, 90% of the applied pesticides enter the various environmental resources as a result of run-off, exposing the farmers as well as consumers of the agricultural produce to severe health issues. Therefore, growing attention has been given toward the development of alternate environmentally friendly pesticides/insecticides that would aid an efficient pest management system and also prevent chronic exposures leading to diseases. One such strategy is, the use of neem plant's (Binomial name: Azadirachta indica) active ingredients which exhibit agro-medicinal properties conferring insecticidal as well as immunomodulatory and anti-cancer properties. The most prominent constituent of neem is azadirachtin, which has been established as a pivotal insecticidal ingredient. It acts as an antifeedant, repellent, and repugnant agent and induces sterility in insects by preventing oviposition and interrupting sperm production in males. This review discusses, key neem pesticidal components, their active functional ingredients along with recent strategies on employing nanocarriers, to provide controlled release of the active ingredients and to improve their stability and sustainability.http://journal.frontiersin.org/article/10.3389/fpls.2017.00610/fullazadirachtinpesticidesbiopesticideAzadirachta indicaagro-medicinal componentsnanocarriers |
| spellingShingle | Suman Chaudhary Rupinder K. Kanwar Alka Sehgal David M. Cahill Colin J. Barrow Rakesh Sehgal Jagat R. Kanwar Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides Frontiers in Plant Science azadirachtin pesticides biopesticide Azadirachta indica agro-medicinal components nanocarriers |
| title | Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides |
| title_full | Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides |
| title_fullStr | Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides |
| title_full_unstemmed | Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides |
| title_short | Progress on Azadirachta indica Based Biopesticides in Replacing Synthetic Toxic Pesticides |
| title_sort | progress on azadirachta indica based biopesticides in replacing synthetic toxic pesticides |
| topic | azadirachtin pesticides biopesticide Azadirachta indica agro-medicinal components nanocarriers |
| url | http://journal.frontiersin.org/article/10.3389/fpls.2017.00610/full |
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