Propolis and Their Active Constituents for Chronic Diseases
Propolis is a mass of chemically diverse phytoconstituents with gummy textures that are naturally produced by honeybees upon collection of plant resins for utilization in various life processes in beehives. Since ancient times, propolis has been a unique traditional remedy globally utilized for seve...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/11/2/259 |
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| author | Vivek P. Chavda Amit Z. Chaudhari Divya Teli Pankti Balar Lalitkumar Vora |
| author_facet | Vivek P. Chavda Amit Z. Chaudhari Divya Teli Pankti Balar Lalitkumar Vora |
| author_sort | Vivek P. Chavda |
| collection | DOAJ |
| description | Propolis is a mass of chemically diverse phytoconstituents with gummy textures that are naturally produced by honeybees upon collection of plant resins for utilization in various life processes in beehives. Since ancient times, propolis has been a unique traditional remedy globally utilized for several purposes, and it has secured value in pharmaceutical and nutraceutical areas in recent years. The chemical composition of propolis comprises diverse constituents and deviations in the precise composition of the honeybee species, plant source used for propolis production by bees, climate conditions and harvesting season. Over 300 molecular structures have been discovered from propolis, and important classes include phenolic acids, flavonoids, terpenoids, benzofurans, benzopyrene and chalcones. Propolis has also been reported to have diverse pharmacological activities, such as antidiabetic, anti-inflammatory, antioxidant, anticancer, immunomodulatory, antibacterial, antiviral, antifungal, and anticaries. As chronic diseases have risen as a global health threat, abundant research has been conducted to track propolis and its constituents as alternative therapies for chronic diseases. Several clinical trials have also revealed the potency of propolis and its constituents for preventing and curing some chronic diseases. This review explores the beneficial effect of propolis and its active constituents with credible mechanisms and computational studies on chronic diseases. |
| first_indexed | 2024-03-11T09:07:37Z |
| format | Article |
| id | doaj.art-ef339d3cc2a3448e9f4d027a7eeac64f |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-11T09:07:37Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-ef339d3cc2a3448e9f4d027a7eeac64f2023-11-16T19:15:32ZengMDPI AGBiomedicines2227-90592023-01-0111225910.3390/biomedicines11020259Propolis and Their Active Constituents for Chronic DiseasesVivek P. Chavda0Amit Z. Chaudhari1Divya Teli2Pankti Balar3Lalitkumar Vora4Department of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad 380008, IndiaDepartment of Pharmaceutical Chemistry, L. M. College of Pharmacy, Ahmedabad 380009, IndiaDepartment of Pharmaceutical Chemistry, L. M. College of Pharmacy, Ahmedabad 380009, IndiaPharmacy Section, L. M. College of Pharmacy, Navrangpura, Ahmedabad 380009, IndiaSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UKPropolis is a mass of chemically diverse phytoconstituents with gummy textures that are naturally produced by honeybees upon collection of plant resins for utilization in various life processes in beehives. Since ancient times, propolis has been a unique traditional remedy globally utilized for several purposes, and it has secured value in pharmaceutical and nutraceutical areas in recent years. The chemical composition of propolis comprises diverse constituents and deviations in the precise composition of the honeybee species, plant source used for propolis production by bees, climate conditions and harvesting season. Over 300 molecular structures have been discovered from propolis, and important classes include phenolic acids, flavonoids, terpenoids, benzofurans, benzopyrene and chalcones. Propolis has also been reported to have diverse pharmacological activities, such as antidiabetic, anti-inflammatory, antioxidant, anticancer, immunomodulatory, antibacterial, antiviral, antifungal, and anticaries. As chronic diseases have risen as a global health threat, abundant research has been conducted to track propolis and its constituents as alternative therapies for chronic diseases. Several clinical trials have also revealed the potency of propolis and its constituents for preventing and curing some chronic diseases. This review explores the beneficial effect of propolis and its active constituents with credible mechanisms and computational studies on chronic diseases.https://www.mdpi.com/2227-9059/11/2/259propolischronic kidney diseaserheumatoid arthritiscancerdiabetesmetabolic syndrome and its associated chronic disease |
| spellingShingle | Vivek P. Chavda Amit Z. Chaudhari Divya Teli Pankti Balar Lalitkumar Vora Propolis and Their Active Constituents for Chronic Diseases Biomedicines propolis chronic kidney disease rheumatoid arthritis cancer diabetes metabolic syndrome and its associated chronic disease |
| title | Propolis and Their Active Constituents for Chronic Diseases |
| title_full | Propolis and Their Active Constituents for Chronic Diseases |
| title_fullStr | Propolis and Their Active Constituents for Chronic Diseases |
| title_full_unstemmed | Propolis and Their Active Constituents for Chronic Diseases |
| title_short | Propolis and Their Active Constituents for Chronic Diseases |
| title_sort | propolis and their active constituents for chronic diseases |
| topic | propolis chronic kidney disease rheumatoid arthritis cancer diabetes metabolic syndrome and its associated chronic disease |
| url | https://www.mdpi.com/2227-9059/11/2/259 |
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