Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease

This study was designed to detect the reactions grossly and histologically on the lymphoid organs (Bursa of Fabricious, Spleen, Thymus) in 8 day old broiler chickens vaccinated with infectious bursal disease vaccine (Intermediate plus)-(Ceva- IBDL).The study revealed no clinical signs on post vaccin...

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Main Authors: S. F. Habash, M. D. Kako
Format: Article
Language:Arabic
Published: University of Mosul, College of Veterinary Medicine 2008-01-01
Series:Iraqi Journal of Veterinary Sciences
Online Access:http://www.vetmedmosul.org/ijvs/media/a4.pdf
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author S. F. Habash
M. D. Kako
author_facet S. F. Habash
M. D. Kako
author_sort S. F. Habash
collection DOAJ
description This study was designed to detect the reactions grossly and histologically on the lymphoid organs (Bursa of Fabricious, Spleen, Thymus) in 8 day old broiler chickens vaccinated with infectious bursal disease vaccine (Intermediate plus)-(Ceva- IBDL).The study revealed no clinical signs on post vaccination days 2, 4 and 6. Gross lesions were swelling of the bursa due to the edema which obviously appeared as yellowish transudate covering the serosal surface area, and the bursa appears congested, the longitudinal striation on the surface become more prominent and congested while small gray foci appear on the surface of spleen. Microscopically there is degeneration and necrosis of lymphocytes in the medullary area and lymphoid follicles, edema between lymphoid follicles, hyperemia, lymphocytic depletion and cystic cavities developed in the medullary area of the follicles. In spleen, there were degeneration and necrosis of reticuloendothelial cells in the germinal center of the white pulp, with hyperemia in spleen and thymus. It was concluded that the intermediate plus vaccine which used in this study induced severe pathological changes in the bursa and spleen and less in the thymus on post vaccination days 2, 4 and 6.
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spelling doaj.art-ef362814a0f742bd8899ce287c36bd372022-12-22T01:54:37ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552008-01-0122 (Arabic)2101109Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal diseaseS. F. HabashM. D. KakoThis study was designed to detect the reactions grossly and histologically on the lymphoid organs (Bursa of Fabricious, Spleen, Thymus) in 8 day old broiler chickens vaccinated with infectious bursal disease vaccine (Intermediate plus)-(Ceva- IBDL).The study revealed no clinical signs on post vaccination days 2, 4 and 6. Gross lesions were swelling of the bursa due to the edema which obviously appeared as yellowish transudate covering the serosal surface area, and the bursa appears congested, the longitudinal striation on the surface become more prominent and congested while small gray foci appear on the surface of spleen. Microscopically there is degeneration and necrosis of lymphocytes in the medullary area and lymphoid follicles, edema between lymphoid follicles, hyperemia, lymphocytic depletion and cystic cavities developed in the medullary area of the follicles. In spleen, there were degeneration and necrosis of reticuloendothelial cells in the germinal center of the white pulp, with hyperemia in spleen and thymus. It was concluded that the intermediate plus vaccine which used in this study induced severe pathological changes in the bursa and spleen and less in the thymus on post vaccination days 2, 4 and 6.http://www.vetmedmosul.org/ijvs/media/a4.pdf
spellingShingle S. F. Habash
M. D. Kako
Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
Iraqi Journal of Veterinary Sciences
title Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
title_full Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
title_fullStr Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
title_full_unstemmed Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
title_short Gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
title_sort gross histological changes in some lymphoid organs in broilers after vaccination against infectious bursal disease
url http://www.vetmedmosul.org/ijvs/media/a4.pdf
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